Protein Alignment Ada and MAPDA

DIOPT Version :10

• Sequence 1: NP_649866.1
• Gene: Ada / 41092
• FlyBaseID: FBgn0037661
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_001311295.1
• Gene: MAPDA / 161823
• HGNCID: 31853
• Length: 355
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 131/335 - (39%)
• Similarity: 200/335 - (59%)
• Gaps: 21/335 - (6%)

  Fly     4 FLKGLPKVELHAHLNGSLGIKSLCDLGERLYGTSCKDFLKLCAHFSRFEK----DMDACFEKFAF 64
            |...|||||||||||||:...::..|      .:.|..||:....:..:|    .::.||:.|..
Human    14 FYSELPKVELHAHLNGSISSHTMKKL------IAQKPDLKIHDQMTVIDKGKKRTLEECFQMFQT 72

  Fly    65 VHELTSTREGLRFATELAIRDFAEDNVQYVEMRTTPKANEN---YSRRDYLQIVIDAIKAASETY 126
            :|:|||:.|.:...|:..|::||:|.|:|:|:|:||: .||   .:::.|::.:::.||.:.:..
Human    73 IHQLTSSPEDILMVTKDVIKEFADDGVKYLELRSTPR-RENATGMTKKTYVESILEGIKQSKQEN 136

  Fly   127 PEITVKLLPSINRAEPVDVAEETVSLAVELARAHPNLILGIDLSGNPGKGRFSDFAPILAQARDK 191
            .:|.|:.|.:::|.....||:|||.||.|...:....:||:||||:|..|:..||...|.:|:..
Human   137 LDIDVRYLIAVDRRGGPLVAKETVKLAEEFFLSTEGTVLGLDLSGDPTVGQAKDFLEPLLEAKKA 201

  Fly   192 GLKLAIHCAEIEN-PSEVKEMLHFGMSRCGHGTFLTPEDIGQL------KQRNIAIECCLTSNVK 249
            |||||:|.:||.| ..|.:.:|.....|.||||||...:.|.|      :|..|.:|.|||||||
Human   202 GLKLALHLSEIPNQKKETQILLDLLPDRIGHGTFLNSGEGGSLDLVDFVRQHRIPLELCLTSNVK 266

  Fly   250 SGTVPSLEEHHLKRIMEADAPKVICTDDSGVFDTTLTKEFLIAAETFGLTREQCIDLTLEAVHHS 314
            |.||||.::||.........|.||||||.|||.|.|::|:.:|||||.||:.|..||:.|::::.
Human   267 SQTVPSYDQHHFGFWYSIAHPSVICTDDKGVFATHLSQEYQLAAETFNLTQSQVWDLSYESINYI 331

  Fly   315 FASEQEQIQM 324
            |||:..:.::
Human   332 FASDSTRSEL 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ada	NP_649866.1	ADA_AMPD	8..327	CDD:238250	130/331 (39%)
MAPDA	NP_001311295.1	ADA_AMPD	18..345	CDD:238250	130/331 (39%)