DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beag and SMU2

DIOPT Version :9

Sequence 1:	NP_649865.1	Gene:	beag / 41091	FlyBaseID:	FBgn0037660	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_180214.1	Gene:	SMU2 / 817187	AraportID:	AT2G26460	Length:	585	Species:	Arabidopsis thaliana

Alignment Length:	608	Identity:	182/608 - (29%)
Similarity:	274/608 - (45%)	Gaps:	174/608 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 KKGQSSSERNDLRRKKKNFYAALKKQEDVKLQEL-SEKYRDRARERRDGANPDYVNVSTPGHGSS 129
            |..:|..:....||:::            ||:|. :.||||||:|||:..||||       ..|.
plant     2 KPSKSHHKEKTARRREE------------KLEESDNPKYRDRAKERRENQNPDY-------DPSE 47

  Fly   130 TNAYRAVAPDMKSGIDAQERRRRIIQESKFLGGDIQHTHLVKGLDYALLQKVRSELHSKEAEEEE 194
            .:::.||||.....|.|.:..:..|:.||:||||::|||||||||||||.|||||:..|...|:
plant    48 LSSFHAVAPPGAVDIRAADALKISIENSKYLGGDVEHTHLVKGLDYALLNKVRSEIVKKPDGED- 111

  Fly   195 IAAAVAREKLAEAAAAAEQLEAERRESEDINAINGALARNIYNLVQARRSKEVPRNELFAPGRMA 259
                      .:....:...|.:|.....|      .|:::|..: .:....:..||:|.||||.
plant   112 ----------GDGGKTSAPKEDQRVTFRTI------AAKSVYQWI-VKPQTIIKSNEMFLPGRMT 159

  Fly   260 YVIDLDDELGESDIPTTLKRSKFEVPVSQEDVATLTTNDIVINKLSQILSYLRAGGRNK--KNKK 322
            :|.|::... ..||||||.|||.:.||.:|.| |:..:..|::::::|:||||.|...|  |.||
plant   160 FVYDMEGGY-THDIPTTLYRSKADCPVPEEFV-TVNVDGSVLDRIAKIMSYLRLGSSGKVLKKKK 222

  Fly   323 RDKD-----KPLFYEKEVENLRGSSSNGGS------------------SRHATSSSS-------- 356
            ::||     ..:..:.:.::.:....||.|                  ..|...|:.
plant   223 KEKDGKGKMSTIANDYDEDDNKSKIENGSSVNISDREVLPPPPPLPPGINHLDLSTKQEEPPVAR 287

  Fly   357 --------------NMGGK---SAPLGDNI------------YDD-----------------IGD 375
                          .:.||   .:|:.:::            :|:                 .|.
plant   288 TDDDDIFVGEGVDYTVPGKDVTQSPISEDMEESPRDKEKVSYFDEPAYGPVQEKVPYFAEPAYGP 352

  Fly   376 YQPSATRPERN------RQEQGKSAPSYFGD----------GPPEASEEPIISSIPPPPKIS--- 421
            .||||.:..::      .|.|| .||.|.|:          |..|...:|.:......|:..
plant   353 VQPSAGQEWQDMSAYGAMQTQG-LAPGYPGEWQEYQYAEQTGYQEQYLQPGMEGYEVQPETDVLL 416

  Fly   422 ----------------------------KAMAARFAEP----EGYAECYPGLEEMNDAIDDSDDE 454
                                        :...||..:|    |.|:|||||.:|.|..|..||:|
plant   417 DPQLMSQEEKDRGLGSVFKRDDQRLQQLRESDAREKDPTFVSESYSECYPGYQEYNHEIVGSDEE 481

  Fly   455 VDYTKMDLGNK-KGPIGRWDFDTQEEYSDYMSTKEALPKAAFQYGVKMQDGRKTRKNKTEKNEKA 518
            .|.:|||:|.| ||.:.||||:|:||:..|...|||:||||||:||||||||||||...::::|
plant   482 PDLSKMDMGGKAKGGLHRWDFETEEEWEKYNEQKEAMPKAAFQFGVKMQDGRKTRKQNRDRDQK- 545

  Fly   519 ELDREWQKIQTIIQKRKLPKDGG 541
             |:.|..:|..|:.::|:.|:||
plant   546 -LNNELHQINKILTRKKMEKEGG 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beag	NP_649865.1	RED_N	87..315	CDD:285099	84/228 (37%)
beag	NP_649865.1	RED_C	434..539	CDD:285098	55/105 (52%)
SMU2	NP_180214.1	RED_N	13..214	CDD:400248	87/239 (36%)
SMU2	NP_180214.1	RED_C	461..567	CDD:400247	56/107 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	134	1.000	Domainoid score	I1634
eggNOG	1	0.900	-	-		E1_KOG2498
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I962
OMA	1	1.010	-	-		QHG59763
OrthoDB	1	1.010	-	-		D500537at2759
OrthoFinder	1	1.000	-	-		FOG0004624
OrthoInspector	1	1.000	-	-		oto3953
orthoMCL	1	0.900	-	-		OOG6_104385
Panther	1	1.100	-	-	LDO	PTHR12765
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4337
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840