Protein Alignment beag and IK

DIOPT Version :10

• Sequence 1: NP_649865.1
• Gene: beag / 41091
• FlyBaseID: FBgn0037660
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_006074.2
• Gene: IK / 3550
• HGNCID: 5958
• Length: 557
• Species: Homo sapiens
• Alignment Length: 614
• Identity: 269/614 - (43%)
• Similarity: 339/614 - (55%)
• Gaps: 156/614 - (25%)

  Fly     3 DAH-LEAPPSV---RLTNDDFRKLLATPRAPPPGSGTSSTSAGGSLATATFATPSTAPGTTGLSG 63
            |.| ::.|.|.   :|||:||||||.||||.|                 |.|.||.       |.
Human    16 DGHDVDDPHSFHQSKLTNEDFRKLLMTPRAAP-----------------TSAPPSK-------SR 56

  Fly    64 EKKKGQSSSERND---LRRKKKNFYAALKKQEDVKLQELSEKYRDRARERRDGANPDYVNVSTPG 125
            ..:..:..:|..|   .|||||::||.|::||..:.:||:|||||||:|||||.|.||......
Human    57 HHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELI- 120

  Fly   126 HGSSTNAYRAVAPDMKSGIDAQERRRRIIQESKFLGGDIQHTHLVKGLDYALLQKVRSELHSKEA 190
              |:|..||||.|..::...|.|:||::||||||||||::|||||||||:|||||||:|:.|||.
Human   121 --STTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEK 183

  Fly   191 EEEEIAAAVAREKLAEAAAAAEQLEAERRESED-INAI--NGALARNIYNLVQARRSKEVPRNEL 252
            ||||:               .|:.:.|.::.|| .|.|  ...|.||:|.::  .:||...||||
Human   184 EEEEL---------------MEKPQKETKKDEDPENKIEFKTRLGRNVYRML--FKSKAYERNEL 231

  Fly   253 FAPGRMAYVIDLDDELGESDIPTTLKRSKFEVPVSQEDVATLTTNDIVINKLSQILSYLRAGGRN 317
            |.|||||||:|||||..::||||||.|||.:.| :.|...|||||||||:||:|||||||.|.||
Human   232 FLPGRMAYVVDLDDEYADTDIPTTLIRSKADCP-TMEAQTTLTTNDIVISKLTQILSYLRQGTRN 295

  Fly   318 KKNKKRDKDKPLFYEKEVENLRGSSSNGGSSRHATSSSSNMGGKSAPLGD-NIYDDIGDYQPSAT 381
            ||.||:||.|                              :..|..|..| ||::|||||.||.|
Human   296 KKLKKKDKGK------------------------------LEEKKPPEADMNIFEDIGDYVPSTT 330

  Fly   382 RPERNRQ-------------------------------------EQGKSAPSYFGDGPPEASEEP 409
            :..|:::                                     |:.|...|||  ..|:..:||
Human   331 KTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYF--EKPKVDDEP 393

  Fly   410 ------------IISSIP---------------PPPKISKAMAARFAEPEGYAECYPGLEEMNDA 447
                        :|.||.               ..|:..|.:...|.....||||||.  .|:|.
Human   394 MDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQLGDFFGMSNSYAECYPA--TMDDM 456

  Fly   448 IDDSDDEVDYTKMDLGNKKGPIGRWDFDTQEEYSDYMSTKEALPKAAFQYGVKMQDGRKTRKNKT 512
            ..|||:||||:|||.||||||:||||||||||||:||:.||||||||||||:||.:|||||:.|
Human   457 AVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFK- 520

  Fly   513 EKNEKAELDREWQKIQTIIQKR-KLPKDG 540
            |.|:||||||:|:||..||:|| |:..||
Human   521 ETNDKAELDRQWKKISAIIEKRKKMEADG 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
beag	NP_649865.1	RED_N	88..315	CDD:462273	123/229 (54%)
		RED_C	434..539	CDD:462272	74/105 (70%)
IK	NP_006074.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..84		32/91 (35%)
		RED_N	84..295	CDD:462273	124/231 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..205		10/38 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	294..403		31/140 (22%)
		17 X 2 AA tandem repeats of R-[ED]	342..375		0/32 (0%)
		RED_C	445..549	CDD:462272	74/106 (70%)