DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Kdm2 and FBXL15

DIOPT Version :9

Sequence 1:NP_001262400.1 Gene:Kdm2 / 41090 FlyBaseID:FBgn0037659 Length:1345 Species:Drosophila melanogaster
Sequence 2:XP_005270206.1 Gene:FBXL15 / 79176 HGNCID:28155 Length:387 Species:Homo sapiens


Alignment Length:159 Identity:49/159 - (30%)
Similarity:74/159 - (46%) Gaps:19/159 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly  1134 QIAKRQLAWLVARLPALKNLSLQNCPIQAVLALHTCL--CPPLQTLDLSFVRGLNDAAIRDILSP 1196
            |:::|.|..|....|.|:.|||.:|.....|||....  ||.|:.|||:..|.|.|.||..:   
Human   213 QLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYL--- 274

  Fly  1197 PKDSRPGLSDSKTRLRDLKVMKLA-GTDISDVAVRYITQSLPYLRHLDLSSCQRITDAGVAQIGT 1260
                      ::.|...|:.:.|| ..::.|.||:.:.::.|.|.||||:.|.|:...||..:..
Human   275 ----------AQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAE 329

  Fly  1261 STTATARLTELNLSACRLVSENALEHLAK 1289
            ....   |..|.:..|..|:|::|..|.|
Human   330 YCPV---LRSLRVRHCHHVAESSLSRLRK 355

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kdm2NP_001262400.1 cupin_like 231..331 CDD:304367
PRTases_typeI <394..>467 CDD:294217
zf-CXXC 670..716 CDD:251032
PHD_4 721..801 CDD:293471
F-box-like <1073..1108 CDD:289689
leucine-rich repeat 1102..1125 CDD:275381
leucine-rich repeat 1126..1149 CDD:275381 4/14 (29%)
leucine-rich repeat 1150..1173 CDD:275381 9/24 (38%)
AMN1 1166..>1320 CDD:187754 37/127 (29%)
leucine-rich repeat 1174..1213 CDD:275381 10/38 (26%)
leucine-rich repeat 1214..1238 CDD:275381 6/24 (25%)
leucine-rich repeat 1239..1267 CDD:275381 9/27 (33%)
leucine-rich repeat 1268..1292 CDD:275381 8/22 (36%)
leucine-rich repeat 1293..1317 CDD:275381
FBXL15XP_005270206.1 F-box 105..>142 CDD:279040
leucine-rich repeat 149..175 CDD:275381
leucine-rich repeat 176..202 CDD:275381
leucine-rich repeat 203..228 CDD:275381 4/14 (29%)
AMN1 <226..>353 CDD:187754 43/142 (30%)
leucine-rich repeat 229..254 CDD:275381 9/24 (38%)
leucine-rich repeat 255..281 CDD:275381 10/38 (26%)
leucine-rich repeat 282..307 CDD:275381 6/24 (25%)
leucine-rich repeat 308..332 CDD:275381 9/23 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.