DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Kdm2 and Fbxl22

DIOPT Version :9

Sequence 1:NP_001262400.1 Gene:Kdm2 / 41090 FlyBaseID:FBgn0037659 Length:1345 Species:Drosophila melanogaster
Sequence 2:NP_780415.1 Gene:Fbxl22 / 74165 MGIID:1921415 Length:236 Species:Mus musculus


Alignment Length:241 Identity:56/241 - (23%)
Similarity:92/241 - (38%) Gaps:64/241 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly  1065 LDPTVLKIIFRYLPQDTLVTCCSVCKVWSNAAVDPDLWKKMNCSEHKMSASLLTAIVRRQPEHLI 1129
            |:...|..:|.:|.:|:..:....|....:...||.||..::.  |.::                
Mouse     6 LNRECLLCLFSFLDKDSRRSLSRTCSQLRDVFEDPTLWPLLHF--HSLA---------------- 52

  Fly  1130 LDWTQIAKRQLAWLVARL-PALKNLSL-------QNCPIQAVL--ALHTCLCPPLQTLDLSFVRG 1184
                ::.|...     || |||::||:       |.|.|:..|  ||...:|...::|       
Mouse    53 ----ELKKDNF-----RLSPALRSLSICWHSSRVQVCSIEDWLKSALQRSICSQHESL------- 101

  Fly  1185 LNDAAIRDILSPPKDSRPGLSDSKTRLRDLKVMKLAGT-DISDVAVRYITQSLPYLRHLDLSSCQ 1248
                 :.|.|....:..|.|:.          :.|:|. .::|..:..:..|.|.||.|.|.:|.
Mouse   102 -----VNDFLLQVCNRCPNLTS----------VTLSGCGHVTDDCLARLLLSCPRLRTLRLENCA 151

  Fly  1249 RITDAGVAQIGTSTTATARLTELNLSACRLVSENALEHL-AKCEGL 1293
            |:|:..:|.:.....|   |..|::..||.||...|..| |.|..|
Mouse   152 RVTNRTLAAVAAHGRA---LQTLHVDFCRNVSAAGLLRLRAACPNL 194

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kdm2NP_001262400.1 cupin_like 231..331 CDD:304367
PRTases_typeI <394..>467 CDD:294217
zf-CXXC 670..716 CDD:251032
PHD_4 721..801 CDD:293471
F-box-like <1073..1108 CDD:289689 8/34 (24%)
leucine-rich repeat 1102..1125 CDD:275381 2/22 (9%)
leucine-rich repeat 1126..1149 CDD:275381 3/23 (13%)
leucine-rich repeat 1150..1173 CDD:275381 10/31 (32%)
AMN1 1166..>1320 CDD:187754 32/130 (25%)
leucine-rich repeat 1174..1213 CDD:275381 5/38 (13%)
leucine-rich repeat 1214..1238 CDD:275381 4/24 (17%)
leucine-rich repeat 1239..1267 CDD:275381 9/27 (33%)
leucine-rich repeat 1268..1292 CDD:275381 10/24 (42%)
leucine-rich repeat 1293..1317 CDD:275381 1/1 (100%)
Fbxl22NP_780415.1 F-box-like 3..43 CDD:403981 8/36 (22%)
LRR 1 15..40 4/24 (17%)
LRR 2 43..72 10/55 (18%)
AMN1 45..>200 CDD:187754 46/202 (23%)
LRR 3 98..123 6/46 (13%)
leucine-rich repeat 116..141 CDD:275381 5/34 (15%)
LRR 4 124..149 7/24 (29%)
leucine-rich repeat 142..167 CDD:275381 8/24 (33%)
LRR 5 150..175 7/27 (26%)
leucine-rich repeat 168..193 CDD:275381 10/24 (42%)
LRR 6 176..201 9/19 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.