DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kdm2 and Fbxl3

DIOPT Version :9

Sequence 1:NP_001262400.1 Gene:Kdm2 / 41090 FlyBaseID:FBgn0037659 Length:1345 Species:Drosophila melanogaster
Sequence 2:NP_001347270.1 Gene:Fbxl3 / 50789 MGIID:1354702 Length:428 Species:Mus musculus


Alignment Length:274 Identity:61/274 - (22%)
Similarity:107/274 - (39%) Gaps:53/274 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly  1062 NLALDPTVLKIIFRYLPQDTLVTCCSVCKVWSNAAVDPDLWKKMNCSEHKMSASLLTAIVRRQPE 1126
            ||..|  ::..:|:|||.........||:.|:.....||||:   |.|.:::....:.:....||
Mouse    38 NLLQD--IVLHVFKYLPLLDRAHASQVCRNWNQVFHMPDLWR---CFEFELNQPATSYLKATHPE 97

  Fly  1127 HLILDWTQIAKR---QLAWLVARLPALKNLSLQNCPIQAVLALHTCLCPPLQTLDLSFVRGLNDA 1188
            .:    .||.||   .|.::..::.:.|..:...|.|.:.|.  .|   .|:||      ||...
Mouse    98 LI----KQIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLV--NC---SLKTL------GLIST 147

  Fly  1189 AIRDILSPPKDS-RPGLSDSKTRLRDLKVMKLAGTDISDVAVR-YITQSLPYLRHLDLSSCQRIT 1251
            |....:..||.. ...|:......:.|..:|:..|.:.|.::: .:..:...|:.|.:|||..::
Mouse   148 ARPSFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVS 212

  Fly  1252 DAGV-----------------------AQIGTSTTATARLTELNLSACRLVSEN-ALEHLAKCEG 1292
            .||:                       ..:..|:....||..|.:.   :|||| ...|....:.
Mouse   213 PAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRID---VVSENPGQTHFHTIQK 274

  Fly  1293 LIW-LDLRHVPQVS 1305
            ..| ..::|.|:|:
Mouse   275 SSWDAFIKHSPKVN 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kdm2NP_001262400.1 cupin_like 231..331 CDD:304367
PRTases_typeI <394..>467 CDD:294217
zf-CXXC 670..716 CDD:251032
PHD_4 721..801 CDD:293471
F-box-like <1073..1108 CDD:289689 11/34 (32%)
leucine-rich repeat 1102..1125 CDD:275381 3/22 (14%)
leucine-rich repeat 1126..1149 CDD:275381 6/25 (24%)
leucine-rich repeat 1150..1173 CDD:275381 5/22 (23%)
AMN1 1166..>1320 CDD:187754 34/167 (20%)
leucine-rich repeat 1174..1213 CDD:275381 9/39 (23%)
leucine-rich repeat 1214..1238 CDD:275381 4/24 (17%)
leucine-rich repeat 1239..1267 CDD:275381 8/50 (16%)
leucine-rich repeat 1268..1292 CDD:275381 7/24 (29%)
leucine-rich repeat 1293..1317 CDD:275381 4/14 (29%)
Fbxl3NP_001347270.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..33
F-box-like 36..77 CDD:315592 13/40 (33%)
LRR 1 119..146 10/37 (27%)
leucine-rich repeat 174..199 CDD:275381 4/24 (17%)
LRR 2 181..207 4/25 (16%)
leucine-rich repeat 200..225 CDD:275381 7/24 (29%)
LRR 3 208..233 3/24 (13%)
LRR 4 234..259 4/27 (15%)
leucine-rich repeat 252..286 CDD:275381 9/36 (25%)
leucine-rich repeat 287..333 CDD:275381 1/2 (50%)
LRR 5 316..341
leucine-rich repeat 334..360 CDD:275381
LRR 6 343..368
leucine-rich repeat 361..383 CDD:275381
LRR 7 369..394
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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