DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kdm2 and Lrrc29

DIOPT Version :9

Sequence 1:NP_001262400.1 Gene:Kdm2 / 41090 FlyBaseID:FBgn0037659 Length:1345 Species:Drosophila melanogaster
Sequence 2:XP_006255593.1 Gene:Lrrc29 / 502201 RGDID:1593150 Length:673 Species:Rattus norvegicus


Alignment Length:328 Identity:76/328 - (23%)
Similarity:131/328 - (39%) Gaps:70/328 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly  1061 QNLALDPTVLKIIFRYLPQDTLVTCCSVCKVW----SNAAVDPDLWKKMNCSEHKMSASLLTAIV 1121
            ::|...|.:|..|..:||.........|.:.|    .||..:.::  :.|......|.|.:.::.
  Rat    53 KHLIFSPQMLTYILSFLPLSDQKEASLVSRAWYYAAQNALRETNV--RYNIPVSSASLSAIKSLG 115

  Fly  1122 RRQPEHLI---LDWTQIAKRQLAWLVARL-PALKNLSL-QNCPIQAVLALHTCLCPPLQTLDLSF 1181
            ||....:.   ||.:..:.:.|..:...| |.|::|.| ...|.:|........||.|:|||||.
  Rat   116 RRGISCISLTNLDGSPASHQVLQSVAYHLGPHLQSLCLGGGSPTEASFLALILGCPVLRTLDLSG 180

  Fly  1182 VRGLNDAAIRDILSPPKDS---RPGLSDSKTRLRDLKVMKLAG-TDISDVAVRYITQSLPYLRHL 1242
            ...|..:.  .:|:.|:.:   |..||.    ||||   .||| .|::|::..:::...|.|..|
  Rat   181 CNSLFTSG--TLLAQPETAQCVRKALSG----LRDL---NLAGLRDLTDLSFNHLSSCFPSLERL 236

  Fly  1243 DLSSCQRITDAGVAQIGTSTTATA----------------------------------------- 1266
            .|:.|....:.|.....||..|::                                         
  Rat   237 SLAYCHLTFELGSTWGSTSPQASSPSQLSFHNLLQFIKERAGTLRALDLSGTGLPPEALQALGQV 301

  Fly  1267 ---RLTELNLSACRLVSENALEHLAKCE-GLIWLDLRHVPQVSTQSVIRFASNSKHDLCVRDIKL 1327
               :|.||||::|:.:|..|:..|.:.: ||..|||....:::.::::. .|...|.|....:|.
  Rat   302 TGLKLEELNLNSCKDLSSEAVATLCRQQPGLTSLDLSGCSELTDRALLA-VSRGLHHLRHLSLKK 365

  Fly  1328 VER 1330
            ::|
  Rat   366 LQR 368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kdm2NP_001262400.1 cupin_like 231..331 CDD:304367
PRTases_typeI <394..>467 CDD:294217
zf-CXXC 670..716 CDD:251032
PHD_4 721..801 CDD:293471
F-box-like <1073..1108 CDD:289689 8/38 (21%)
leucine-rich repeat 1102..1125 CDD:275381 5/22 (23%)
leucine-rich repeat 1126..1149 CDD:275381 4/26 (15%)
leucine-rich repeat 1150..1173 CDD:275381 6/23 (26%)
AMN1 1166..>1320 CDD:187754 48/202 (24%)
leucine-rich repeat 1174..1213 CDD:275381 13/41 (32%)
leucine-rich repeat 1214..1238 CDD:275381 6/24 (25%)
leucine-rich repeat 1239..1267 CDD:275381 8/71 (11%)
leucine-rich repeat 1268..1292 CDD:275381 9/24 (38%)
leucine-rich repeat 1293..1317 CDD:275381 5/23 (22%)
Lrrc29XP_006255593.1 leucine-rich repeat 124..142 CDD:275381 3/17 (18%)
LRR_RI <170..410 CDD:238064 51/209 (24%)
leucine-rich repeat 173..206 CDD:275381 11/34 (32%)
leucine-rich repeat 207..232 CDD:275381 9/27 (33%)
leucine-rich repeat 233..279 CDD:275381 8/45 (18%)
leucine-rich repeat 280..300 CDD:275381 0/19 (0%)
AMN1 292..480 CDD:187754 19/78 (24%)
leucine-rich repeat 306..331 CDD:275381 9/24 (38%)
leucine-rich repeat 332..357 CDD:275381 5/25 (20%)
leucine-rich repeat 358..439 CDD:275381 3/11 (27%)
leucine-rich repeat 383..408 CDD:275381
leucine-rich repeat 413..437 CDD:275381
leucine-rich repeat 440..465 CDD:275381
leucine-rich repeat 466..526 CDD:275381
leucine-rich repeat 527..577 CDD:275381
AMN1 <564..>638 CDD:187754
leucine-rich repeat 578..603 CDD:275381
leucine-rich repeat 604..629 CDD:275381
leucine-rich repeat 630..655 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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