DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kdm2 and fbxl15

DIOPT Version :9

Sequence 1:NP_001262400.1 Gene:Kdm2 / 41090 FlyBaseID:FBgn0037659 Length:1345 Species:Drosophila melanogaster
Sequence 2:NP_998107.1 Gene:fbxl15 / 405878 ZFINID:ZDB-GENE-040426-2440 Length:296 Species:Danio rerio


Alignment Length:296 Identity:72/296 - (24%)
Similarity:120/296 - (40%) Gaps:56/296 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly  1056 HYSSSQNLALDPTVLKIIFRYLPQDTLVTCCSV--------------CKVWSNAAVDPDLWKK-- 1104
            |.....:|..:..::..:|.:||...||:...|              |:.:..|...|.:.::  
Zfish    12 HRCELLDLPWEDVLVSHVFCHLPLRLLVSLQRVSKSFRSLIQVYLDNCRTFDPAQTGPHIPREAF 76

  Fly  1105 ---------------MNCSEHKMSASLLTAIVRRQP-EHLIL-DWTQIAKRQLAWLVARLPALKN 1152
                           .|||:......||..|.:.|. :|:.| ...|:::|.|..:....|.|::
Zfish    77 CSILRHNQVLQHLSVTNCSDWITDTDLLPVIGQNQQLQHVDLRGCAQLSRRALVAVSLSCPRLQH 141

  Fly  1153 LSLQNCPIQAVLALHTCL--CPPLQTLDLSFVRGLNDAAIRDILSPPKDSRPGLSDSKTRLRDLK 1215
            |||.:|.....|||.:..  ||.|::|||:..|.|.|.|:           ..|:.....||.|.
Zfish   142 LSLAHCEWVDSLALRSLADHCPMLRSLDLTACRQLKDPAV-----------CYLAGKCPELRALS 195

  Fly  1216 VMKLAGTDISDVAVRYITQSLPYLRHLDLSSCQRITDAGVAQIGTSTTATARLTELNLSACRLVS 1280
            |  ....:|:|.||..:.:....:..|||:.|.|:.:..   |.|......:|..|.::.|..|:
Zfish   196 V--AVNANITDTAVEEVAKKCREMERLDLTGCLRVRNEA---IRTLAEYCPKLQSLKVNHCHNVT 255

  Fly  1281 ENALEHLAKCEGLIWLDLRHVPQ---VSTQSVIRFA 1313
            |::|..|.:..  :.:|:....|   |..|.|:.||
Zfish   256 ESSLGVLRRRN--VEIDVEPPLQRALVLLQDVVGFA 289

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kdm2NP_001262400.1 cupin_like 231..331 CDD:304367
PRTases_typeI <394..>467 CDD:294217
zf-CXXC 670..716 CDD:251032
PHD_4 721..801 CDD:293471
F-box-like <1073..1108 CDD:289689 10/65 (15%)
leucine-rich repeat 1102..1125 CDD:275381 6/39 (15%)
leucine-rich repeat 1126..1149 CDD:275381 5/23 (22%)
leucine-rich repeat 1150..1173 CDD:275381 9/24 (38%)
AMN1 1166..>1320 CDD:187754 41/153 (27%)
leucine-rich repeat 1174..1213 CDD:275381 10/38 (26%)
leucine-rich repeat 1214..1238 CDD:275381 6/23 (26%)
leucine-rich repeat 1239..1267 CDD:275381 7/27 (26%)
leucine-rich repeat 1268..1292 CDD:275381 7/23 (30%)
leucine-rich repeat 1293..1317 CDD:275381 7/24 (29%)
fbxl15NP_998107.1 F-box 16..>52 CDD:279040 7/35 (20%)
leucine-rich repeat 51..85 CDD:275381 3/33 (9%)
leucine-rich repeat 86..112 CDD:275381 6/25 (24%)
AMN1 <111..272 CDD:187754 49/178 (28%)
leucine-rich repeat 113..138 CDD:275381 5/24 (21%)
LRR 1 138..159 8/20 (40%)
leucine-rich repeat 139..164 CDD:275381 9/24 (38%)
LRR 2 164..185 8/31 (26%)
leucine-rich repeat 165..190 CDD:275381 9/35 (26%)
LRR 3 190..211 8/22 (36%)
leucine-rich repeat 191..216 CDD:275381 8/26 (31%)
LRR 4 216..237 7/23 (30%)
leucine-rich repeat 217..242 CDD:275381 7/27 (26%)
LRR 5 242..263 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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