Protein Alignment Kdm2 and kdm7aa

DIOPT Version :9

• Sequence 1: NP_001262400.1
• Gene: Kdm2 / 41090
• FlyBaseID: FBgn0037659
• Length: 1345
• Species: Drosophila melanogaster
• Sequence 2: NP_001333080.1
• Gene: kdm7aa / 321248
• ZFINID: ZDB-GENE-030131-9829
• Length: 837
• Species: Danio rerio
• Alignment Length: 1049
• Identity: 253/1049 - (24%)
• Similarity: 402/1049 - (38%)
• Gaps: 346/1049 - (32%)

  Fly    34 PNAKGVQRRQLRERKQRKLYLEEWSLGD--EDGEGTR----GFSV-AEKLESSKFAQAGMVREMR 91
            ||.:.:....:.::.      ..|...|  |..:|||    |.:| .::|::..||...::.:|:
Zfish    51 PNCEPIHGPYMMKKH------NNWHRHDYTEPNDGTRPVQAGTAVFVKELQARSFASGDILVQMQ 109

  Fly    92 GCDLTVAFLQQHGFNIPLLFRDKAGLGLRMPDPQEFTVNDVRLCVGSRRLLDVMDVNTQKNLQMT 156
            |..:|..||::.|||.|::..|..||||::| |..|:|:||...||:.:::||:||..|.:.:|.
Zfish   110 GNQVTKRFLEKEGFNYPIVVHDLDGLGLKLP-PPSFSVSDVEHYVGANKVIDVIDVAKQADSKMK 173

  Fly   157 MKEWQQYYDSPQKDRLLNVISLEFSHTRLDRFVQSPEIVRQIDWVDVVWPKQLKDAQREGTNLLG 221
            :.|:.:||..|::.::|||||||||.||:...|..|:|.:::.||:..||..
Zfish   174 LGEFVKYYYQPERPKVLNVISLEFSDTRMSNLVVVPDIAQKMSWVENYWPDD------------- 225

  Fly   222 GMMYPK--VQKYCLMSVKNCYTDFHIDFGGTSVWYHILRGSKVFWLIPPTDRNLQLYEKWVLSGK 284
             ..:||  |||||||.:||.||||||||||||||||:|.|.|:|:||.||..||.|||.|..|..
Zfish   226 -SFFPKPFVQKYCLMGMKNSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTKANLALYEAWSSSPN 289

  Fly   285 QADIFFGDTVEKCARVYLTAGNTFFIPTGWIHAVYTPTQSLVFGGNFLHSFGIVKQLKTASVEDS 349
            |:::|||:.|:||.:..:..|.|..:||||||||.|...|:.|||||||:..|..||:...:|..
Zfish   290 QSEVFFGEKVDKCYKCVVKQGTTILLPTGWIHAVLTSQDSMAFGGNFLHNLNIDMQLRCYEMERR 354

  Fly   350 TKVPQKFRYPFFTEMLWYVLARYVHTLLGHSHLEGEASLSEDEMAARPHTHLTHHELFGLKEIVM 414
            .|.|..|::|:|..:.|||
Zfish   355 LKTPDLFKFPYFEAICWYV---------------------------------------------- 373

  Fly   415 YLYDLPPQKKNVPSLVLDPVALIKDVRSLVERHCKDQQDLAITGVSVLKSPPGSQPPFLLYDRTR 479
                    .||          |::.::.|.|..| :.|...:.||..|.|              .
Zfish   374 --------AKN----------LLETLKELRENKC-EAQGFLVNGVKALIS--------------S 405

  Fly   480 VKQEIKQEIARKNAEV---IREQQQLEA--GRAREAESDTSQSTGVGSVIGMGAGVEYSNGVMKK 539
            :|..:::|:.:.|:||   ||....::|  ...|..|.|::::      :......|.|   :.:
Zfish   406 LKMWLRRELTQPNSEVPDNIRPGHLIKALSKEIRHLEDDSNKA------VKTQGSAECS---LSR 461

  Fly   540 EQLENGSGVTVGG--------------------------HGSQ--PEATFALPTDTLKYRPPKKM 576
            ..||.|.......                          |.|:  |.....|...||:..  |::
Zfish   462 STLEKGDQAQQAARRLQDHHHHRRRHHHHHHHHHHHHHHHHSRKLPSNLDVLELHTLEVL--KRL 524

  Fly   577 HLATALVAAAASSSSGGGGPVAGVGGSAVVGSSHSPT------GGGV----GPVTGAGGAISVIA 631
            .:......:|.||...|.........:|.|.:||...      .|.:    .|:|.....::.:
Zfish   525 EVGQLKEDSAFSSKVNGKFKKVCPVPAAAVEASHDNALRLVMCNGKIIRERMPITNVAATVNAV- 588

  Fly   632 TSSSYIEGGQVGGILNMDNCHSPEGGGAKLSPNLTGTGQPRRRRTRCKNCAACQRSDCGTCPFCM 696
                           .|.:.|..:.....:.|      :.:.::.:|::
Zfish   589 ---------------EMYHKHRIKLERIPMCP------EEKVKKEKCED---------------- 616

  Fly   697 DMVKFGGPGRAKQTCMMRQCLSPMLPVTAQCVYCHLDGWRQTPVSPQTKQLASADGPSALMECSV 761
               :||      ..|.:::.:|....|             ||.:..::..|||:|..|.
Zfish   617 ---EFG------VQCTIKKPVSQGESV-------------QTELRTESPHLASSDSDSK------ 653

  Fly   762 CYEIAHPDCALSQLDGTEDAADAKGIVNEDLPNSWECPSCCRSGKNYDYKPRHFRARQKSSEVRR 826
                            ..|:|:...:.:|.
Zfish   654 ----------------AGDSAEKCSLESES----------------------------------- 667

  Fly   827 VSVSHGQGGAEGHADGNTLLPPPVGQYNDFVFTSESEMESGTVSGHMTHWKHGMKRHHQLEVKTE 891
               |.|:.|.                         |:.:|||...|:...:|.   ||:..:|.|
Zfish   668 ---SDGEDGG-------------------------SQRDSGTFVEHLNSHRHS---HHKQALKRE 701

  Fly   892 RNNSCDTP---------SPGISPNAIGGDSKVGKRR---KSDDGTSVSSS--MHESNDAPCGSSA 942
            |..|.:|.         :..:.|.|.||.:.:.::|   ...:|:|.|||  |.:|:: ||
Zfish   702 RPTSPNTDCAIQGMLSMAGLLCPQASGGAADILQQRWWASQGNGSSTSSSSDMWDSSE-PC---- 761

  Fly   943 EGAGGAGNANVSTNQWSGSGGGGGSRKKNSIRSQLAQQMLNSSTRVLKKPQYVVRPASGTGSSSS 1007
                   :|..|.:...||.|     ::.|.|.......|:.|.|....|    .|.|...:...
Zfish   762 -------SAPRSPDAEDGSLG-----EEYSYRESSLSPPLHPSKRHAPNP----TPVSNQATKGK 810

  Fly  1008 SGNGGSASA 1016
            ....|.|:|
Zfish   811 RPKKGQATA 819

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kdm2	NP_001262400.1	cupin_like	231..331	CDD:304367	59/99 (60%)
		PRTases_typeI	<394..>467	CDD:294217	11/72 (15%)
		zf-CXXC	670..716	CDD:251032	4/45 (9%)
		PHD_4	721..801	CDD:293471	11/79 (14%)
		F-box-like	<1073..1108	CDD:289689
		leucine-rich repeat	1102..1125	CDD:275381
		leucine-rich repeat	1126..1149	CDD:275381
		leucine-rich repeat	1150..1173	CDD:275381
		AMN1	1166..>1320	CDD:187754
		leucine-rich repeat	1174..1213	CDD:275381
		leucine-rich repeat	1214..1238	CDD:275381
		leucine-rich repeat	1239..1267	CDD:275381
		leucine-rich repeat	1268..1292	CDD:275381
		leucine-rich repeat	1293..1317	CDD:275381
kdm7aa	NP_001333080.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	442..506		9/72 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	629..710		28/181 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	742..820		25/99 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000253
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910