DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kdm2 and Fbxl13

DIOPT Version :9

Sequence 1:NP_001262400.1 Gene:Kdm2 / 41090 FlyBaseID:FBgn0037659 Length:1345 Species:Drosophila melanogaster
Sequence 2:XP_011248071.1 Gene:Fbxl13 / 320118 MGIID:2443416 Length:889 Species:Mus musculus


Alignment Length:283 Identity:64/283 - (22%)
Similarity:113/283 - (39%) Gaps:57/283 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly  1060 SQNLALDPTVLK-----IIFRYLPQDTLVTCCSVCKVWSNAAVDPDLWKKMNCSEHKMSASLLTA 1119
            ::.:|.|.:||.     .||.||....::.|..|.:.|........||..::.|..|..|.....
Mouse   233 NRRIAFDISVLPEQAILQIFLYLTFKDMMACSRVNRSWMAMIQRGSLWNSIDFSTVKNIADKCVV 297

  Fly  1120 IVRRQPEHLILDWTQIAKRQLAWLVARLPALKNLSLQNCPIQAVLALHTCLCPPLQTLDLSFVRG 1184
                         |.:.|    |   ||..|: |:.:.|..:.........|..||.|::|..:.
Mouse   298 -------------TTLQK----W---RLNVLR-LNFRGCDFRTKTLKAVSHCKNLQELNVSDCQS 341

  Fly  1185 LNDAAIRDILSPPKDSRPGLSDSKTRLRDLKVMKLAGTDISDVAVRYITQSLPYLRHLDLSSCQR 1249
            ..|.::|.|    .:..||          :..:.|:.|.|::..:|.:.:....|::|.|:.|::
Mouse   342 FTDESMRHI----SEGCPG----------VLYLNLSNTTITNRTMRLLPRYFHNLQNLSLAYCRK 392

  Fly  1250 ITDAGVAQIGTSTTATARLTELNLSACRLVSENALEHLA-KCEGLIWLDLRHVPQVSTQSVIRFA 1313
            .||.|:..:... ....:|..|:||.|..:|.....::| .|.|::.|.:..:|.::        
Mouse   393 FTDKGLQYLNLG-NGCHKLIYLDLSGCTQISVQGFRNIASSCTGIVHLTINDMPTLT-------- 448

  Fly  1314 SNSKHDLCVRDIKLVERRRRNST 1336
                 |.||:  .|||:..|.|:
Mouse   449 -----DNCVK--VLVEKCPRISS 464

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kdm2NP_001262400.1 cupin_like 231..331 CDD:304367
PRTases_typeI <394..>467 CDD:294217
zf-CXXC 670..716 CDD:251032
PHD_4 721..801 CDD:293471
F-box-like <1073..1108 CDD:289689 9/34 (26%)
leucine-rich repeat 1102..1125 CDD:275381 4/22 (18%)
leucine-rich repeat 1126..1149 CDD:275381 5/22 (23%)
leucine-rich repeat 1150..1173 CDD:275381 4/22 (18%)
AMN1 1166..>1320 CDD:187754 32/154 (21%)
leucine-rich repeat 1174..1213 CDD:275381 9/38 (24%)
leucine-rich repeat 1214..1238 CDD:275381 4/23 (17%)
leucine-rich repeat 1239..1267 CDD:275381 7/27 (26%)
leucine-rich repeat 1268..1292 CDD:275381 8/24 (33%)
leucine-rich repeat 1293..1317 CDD:275381 2/23 (9%)
Fbxl13XP_011248071.1 F-box-like 240..284 CDD:372399 11/43 (26%)
leucine-rich repeat 255..268 CDD:275381 3/12 (25%)
leucine-rich repeat 280..306 CDD:275381 8/45 (18%)
AMN1 306..475 CDD:187754 43/190 (23%)
leucine-rich repeat 307..330 CDD:275381 4/23 (17%)
leucine-rich repeat 331..356 CDD:275381 7/28 (25%)
leucine-rich repeat 357..381 CDD:275381 4/23 (17%)
leucine-rich repeat 382..409 CDD:275381 7/27 (26%)
leucine-rich repeat 410..435 CDD:275381 8/24 (33%)
leucine-rich repeat 436..461 CDD:275381 8/39 (21%)
leucine-rich repeat 462..484 CDD:275381 1/3 (33%)
AMN1 473..605 CDD:187754
leucine-rich repeat 486..511 CDD:275381
leucine-rich repeat 512..536 CDD:275381
leucine-rich repeat 537..564 CDD:275381
leucine-rich repeat 565..590 CDD:275381
leucine-rich repeat 591..610 CDD:275381
leucine-rich repeat 617..645 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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