DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kdm2 and Fbxl15

DIOPT Version :9

Sequence 1:NP_001262400.1 Gene:Kdm2 / 41090 FlyBaseID:FBgn0037659 Length:1345 Species:Drosophila melanogaster
Sequence 2:NP_001101073.1 Gene:Fbxl15 / 309453 RGDID:1306444 Length:300 Species:Rattus norvegicus


Alignment Length:219 Identity:59/219 - (26%)
Similarity:94/219 - (42%) Gaps:30/219 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly  1077 LPQDTLVTCCSVCKVWSNAAVDPDLWKKMNCSEHKMSASLLTAIVRRQPE---HLILDWTQIAKR 1138
            :|:..||......:.....|:.|       |.|..:...|: .::.|.|:   ..:....|:::|
  Rat    74 IPRAALVRLLRDAEG
LQELALAP-------CHEWLLDEDLV-PVLARNPQLRSVALAGCGQLSRR 130

  Fly  1139 QLAWLVARLPALKNLSLQNCPIQAVLALHTCL--CPPLQTLDLSFVRGLNDAAIRDILSPPKDSR 1201
            .|..|....|.|:.:||.:|.....|||....  ||.|:.|||:..|.|.|.||..:        
  Rat   131 ALGALAEGCPRLQRISLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYL-------- 187

  Fly  1202 PGLSDSKTRLRDLKVMKLA-GTDISDVAVRYITQSLPYLRHLDLSSCQRITDAGVAQIGTSTTAT 1265
                 ::.|...|:.:.|| ..::.|.||:.:.::.|.|.||||:.|.|:...||..:.....| 
  Rat   188 -----AQRRGAGLRSLSLAVNANVGDTAVQELARNCPQLEHLDLTGCLRVGSDGVRTLAEYCPA- 246

  Fly  1266 ARLTELNLSACRLVSENALEHLAK 1289
              |..|.:..|..|:|.:|..|.|
  Rat   247 --LRSLRVRHCHHVAEPSLSRLRK 268

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kdm2NP_001262400.1 cupin_like 231..331 CDD:304367
PRTases_typeI <394..>467 CDD:294217
zf-CXXC 670..716 CDD:251032
PHD_4 721..801 CDD:293471
F-box-like <1073..1108 CDD:289689 5/30 (17%)
leucine-rich repeat 1102..1125 CDD:275381 4/22 (18%)
leucine-rich repeat 1126..1149 CDD:275381 4/25 (16%)
leucine-rich repeat 1150..1173 CDD:275381 8/24 (33%)
AMN1 1166..>1320 CDD:187754 38/127 (30%)
leucine-rich repeat 1174..1213 CDD:275381 10/38 (26%)
leucine-rich repeat 1214..1238 CDD:275381 6/24 (25%)
leucine-rich repeat 1239..1267 CDD:275381 10/27 (37%)
leucine-rich repeat 1268..1292 CDD:275381 8/22 (36%)
leucine-rich repeat 1293..1317 CDD:275381
Fbxl15NP_001101073.1 F-box 18..55 CDD:395521
leucine-rich repeat 62..88 CDD:275381 3/13 (23%)
leucine-rich repeat 89..115 CDD:275381 6/33 (18%)
Interaction with SMURF1. /evidence=ECO:0000250 113..269 50/172 (29%)
leucine-rich repeat 116..141 CDD:275381 4/24 (17%)
AMN1 <139..>268 CDD:187754 44/144 (31%)
leucine-rich repeat 142..167 CDD:275381 8/24 (33%)
leucine-rich repeat 168..194 CDD:275381 10/38 (26%)
leucine-rich repeat 195..220 CDD:275381 6/24 (25%)
leucine-rich repeat 221..245 CDD:275381 9/23 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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