DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kdm2 and Fbxl12

DIOPT Version :9

Sequence 1:NP_001262400.1 Gene:Kdm2 / 41090 FlyBaseID:FBgn0037659 Length:1345 Species:Drosophila melanogaster
Sequence 2:NP_001273458.1 Gene:Fbxl12 / 30843 MGIID:1354738 Length:349 Species:Mus musculus


Alignment Length:283 Identity:66/283 - (23%)
Similarity:102/283 - (36%) Gaps:68/283 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly  1075 RYLPQDTLV----TCCSVCKVWSNAAVDPDLWKKMNCSEHKMSASLLTAIVRRQPEHLILDWTQI 1135
            |.||..|::    ..|.||..|.....|..||:.::.:.:.|...::..::||            
Mouse    36 RLLPSQTILLPRNPGCRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLLRR------------ 88

  Fly  1136 AKRQLAWLVARL-------------------PALKNLSLQNCPIQAVLALH---------TCLCP 1172
                  ::.:||                   |||.....|.||....|.||         |.|..
Mouse    89 ------YMASRLYSLRMGGYLFSGSQAPQLSPALMRALGQKCPNLKRLCLHVADLSMVPITSLPS 147

  Fly  1173 PLQTLDLS-------FVRGLNDAAIRDILS-PPKDSRPGLSDSK----TRLRDLKVMKLAGT-DI 1224
            .|:||:|.       :::...|..:..:|. ...|..|...|..    ||.|.|:.:.|.|| .:
Mouse   148 TLRTLELHSCEISMIWLQKEQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRSLVLGGTYRV 212

  Fly  1225 SDVAVRYITQSLPYLRHLDLSSCQRITDAGVAQIG--TSTTATARLTELNLSACRLVSENALEHL 1287
            ::..:....|.|.||:.|::..|....|:.:..|.  .......|||...|||..||   .||.:
Mouse   213 TETGLDASLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKIRLTVGGLSAQGLV---FLEGM 274

  Fly  1288 AKCEGLIWLDLRHVPQVSTQSVI 1310
            ...|.|.:......|.:.|.:.|
Mouse   275 PVLESLCFQGPLITPDMPTPTQI 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kdm2NP_001262400.1 cupin_like 231..331 CDD:304367
PRTases_typeI <394..>467 CDD:294217
zf-CXXC 670..716 CDD:251032
PHD_4 721..801 CDD:293471
F-box-like <1073..1108 CDD:289689 11/36 (31%)
leucine-rich repeat 1102..1125 CDD:275381 4/22 (18%)
leucine-rich repeat 1126..1149 CDD:275381 2/41 (5%)
leucine-rich repeat 1150..1173 CDD:275381 9/31 (29%)
AMN1 1166..>1320 CDD:187754 43/169 (25%)
leucine-rich repeat 1174..1213 CDD:275381 11/50 (22%)
leucine-rich repeat 1214..1238 CDD:275381 6/24 (25%)
leucine-rich repeat 1239..1267 CDD:275381 5/29 (17%)
leucine-rich repeat 1268..1292 CDD:275381 9/23 (39%)
leucine-rich repeat 1293..1317 CDD:275381 4/18 (22%)
Fbxl12NP_001273458.1 F-box-like <51..73 CDD:289689 7/21 (33%)
leucine-rich repeat 127..148 CDD:275381 5/20 (25%)
AMN1 144..>249 CDD:187754 25/104 (24%)
leucine-rich repeat 149..175 CDD:275381 5/25 (20%)
leucine-rich repeat 176..200 CDD:275381 6/23 (26%)
leucine-rich repeat 201..226 CDD:275381 6/24 (25%)
leucine-rich repeat 227..252 CDD:275381 5/24 (21%)
leucine-rich repeat 253..276 CDD:275381 10/25 (40%)
leucine-rich repeat 277..306 CDD:275381 5/21 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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