| Sequence 1: | NP_001262400.1 | Gene: | Kdm2 / 41090 | FlyBaseID: | FBgn0037659 | Length: | 1345 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036440.1 | Gene: | KDM2A / 22992 | HGNCID: | 13606 | Length: | 1162 | Species: | Homo sapiens |
| Alignment Length: | 1405 | Identity: | 470/1405 - (33%) |
|---|---|---|---|
| Similarity: | 642/1405 - (45%) | Gaps: | 351/1405 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 32 LSPNAKGVQRRQLRERKQRKLYLEEWSLGDEDGEGTRGFSVAEKLESSKFAQAGMVREMRGCDLT 96
Fly 97 VAFLQQHGFNIPLLFRDKAGLGLRMPDPQEFTVNDVRLCVGSRRLLDVMDVNTQKNLQMTMKEWQ 161
Fly 162 QYYDSPQKDR--LLNVISLEFSHTRLDRFVQSPEIVRQIDWVDVVWPKQLKDAQREGTNLLGGMM 224
Fly 225 YPKVQKYCLMSVKNCYTDFHIDFGGTSVWYHILRGSKVFWLIPPTDRNLQLYEKWVLSGKQADIF 289
Fly 290 FGDTVEKCARVYLTAGNTFFIPTGWIHAVYTPTQSLVFGGNFLHSFGIVKQLKTASVEDSTKVPQ 354
Fly 355 KFRYPFFTEMLWYVLARYVHTLLGHSHLEGE---ASLSED------------------------- 391
Fly 392 ------------------------------------------------------EMAARP--HTH 400
Fly 401 LTHHELFGLKEIVMYLYDLPPQKKNVPSLVLDPVALIKDVRSLVERHCKDQQDLAITGVSVLKSP 465
Fly 466 PGSQPPFLLYDRTRVKQEIKQEIARKNAEVIREQQQLEAGRAREAESDTSQSTGVGSVIGMGAGV 530
Fly 531 EYSNGVMKKEQLENGSGVTVGGHGSQPEATFALPTDTLKYRPPKKMHLATALVAAAASSSSGGGG 595
Fly 596 PVAGVGGSAVVGSSHSPTGGGVGPVTGAGGAISVIATSSSYIEGGQVGGILNMDNCHSPEGGGAK 660
Fly 661 LSPNLTGTGQPRRRRTRCKNCAACQRSDCGTCPFCMDMVKFGGPGRAKQTCMMRQCLSPMLPVTA 725
Fly 726 QCVYC-HLDGWRQTPVSPQTKQLASADGPSALMECSVCYEIAHPDCALSQLDGTEDAADAKGIVN 789
Fly 790 EDLPNSWECPSCCRSGKNYDYKPRHFRARQKSSEVRRVSVSHGQGGAEGHADGNTLLPPPVGQYN 854
Fly 855 DFVFTSESEMESGTVS--GHMTHWKHGMKRHHQLEVKTERNNSCDTPSPGISP---NAIGGDSKV 914
Fly 915 GKRRKSDDGTSVSSSMHESNDAPCG----SSAEGAGGAGNANVSTNQWSGSGGGGGSRKKNSIRS 975
Fly 976 QLAQQMLNSSTRVLKKPQYVVR--PASGTGSSSSSGNGGSASATNGISNGSNQSGANSCGAGNGE 1038
Fly 1039 RGTNNGGLSGSNGLGNQHYSSSQNLALDPTVLKIIFRYLPQDTLVTCCSVCKVWSNAAVDPDLWK 1103
Fly 1104 KMNCSEHK-MSASLLTAIVRRQPEHLILDWTQIAKRQLAWLVARLPALKNLSLQNCPIQAVLALH 1167
Fly 1168 TCLCPPLQTLDLSFVRGLNDAAIRDILSPPKDSRPGLSDSKTRLRDLKVMKLAGTDISDVAVRYI 1232
Fly 1233 TQSLPYLRHLDLSSCQRITDAG---VAQIGTSTTATARLTELNLSACRLVSENALEHLAKCEGLI 1294
Fly 1295 WLDLRHVPQVSTQSVIRFAS----NSKHDLCVRDIKLVER 1330 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Kdm2 | NP_001262400.1 | cupin_like | 231..331 | CDD:304367 | 73/99 (74%) |
| PRTases_typeI | <394..>467 | CDD:294217 | 32/74 (43%) | ||
| zf-CXXC | 670..716 | CDD:251032 | 26/45 (58%) | ||
| PHD_4 | 721..801 | CDD:293471 | 30/80 (38%) | ||
| F-box-like | <1073..1108 | CDD:289689 | 14/34 (41%) | ||
| leucine-rich repeat | 1102..1125 | CDD:275381 | 7/23 (30%) | ||
| leucine-rich repeat | 1126..1149 | CDD:275381 | 13/22 (59%) | ||
| leucine-rich repeat | 1150..1173 | CDD:275381 | 11/22 (50%) | ||
| AMN1 | 1166..>1320 | CDD:187754 | 59/160 (37%) | ||
| leucine-rich repeat | 1174..1213 | CDD:275381 | 18/38 (47%) | ||
| leucine-rich repeat | 1214..1238 | CDD:275381 | 8/23 (35%) | ||
| leucine-rich repeat | 1239..1267 | CDD:275381 | 11/30 (37%) | ||
| leucine-rich repeat | 1268..1292 | CDD:275381 | 8/23 (35%) | ||
| leucine-rich repeat | 1293..1317 | CDD:275381 | 7/27 (26%) | ||
| KDM2A | NP_036440.1 | cupin_like | 199..299 | CDD:328732 | 73/99 (74%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 367..389 | 0/21 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 532..557 | 8/121 (7%) | |||
| zf-CXXC | <576..609 | CDD:251032 | 19/32 (59%) | ||
| PHD_KDM2A | 619..675 | CDD:277113 | 28/75 (37%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 704..789 | 20/118 (17%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 839..887 | 10/61 (16%) | |||
| F-box-like | 896..934 | CDD:315592 | 15/37 (41%) | ||
| leucine-rich repeat | 930..954 | CDD:275381 | 7/23 (30%) | ||
| AMN1 | 932..1138 | CDD:332986 | 85/209 (41%) | ||
| leucine-rich repeat | 955..978 | CDD:275381 | 13/22 (59%) | ||
| LRR 1 | 961..982 | 14/20 (70%) | |||
| leucine-rich repeat | 979..1002 | CDD:275381 | 11/22 (50%) | ||
| LRR 2 | 984..1010 | 14/25 (56%) | |||
| leucine-rich repeat | 1003..1040 | CDD:275381 | 18/38 (47%) | ||
| leucine-rich repeat | 1041..1065 | CDD:275381 | 8/23 (35%) | ||
| LRR 3 | 1048..1073 | 11/24 (46%) | |||
| leucine-rich repeat | 1066..1095 | CDD:275381 | 11/28 (39%) | ||
| LRR 4 | 1074..1103 | 11/30 (37%) | |||
| leucine-rich repeat | 1096..1120 | CDD:275381 | 8/23 (35%) | ||
| LRR 5 | 1104..1128 | 5/23 (22%) | |||
| leucine-rich repeat | 1121..1140 | CDD:275381 | 4/18 (22%) | ||
| LRR 6 | 1129..1156 | 7/28 (25%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 255 | 1.000 | Domainoid score | I2050 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG1633 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H56564 | |
| Inparanoid | 1 | 1.050 | 814 | 1.000 | Inparanoid score | I484 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S3167 |
| OMA | 1 | 1.010 | - | - | QHG50015 | |
| OrthoDB | 1 | 1.010 | - | - | D165446at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000253 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41017 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104082 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR23123 |
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R626 |
| SonicParanoid | 1 | 1.000 | - | - | X1005 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.910 | |||||