Protein Alignment Rel and relb

DIOPT Version :10

• Sequence 1: NP_477094.1
• Gene: Rel / 41087
• FlyBaseID: FBgn0014018
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: XP_021322023.1
• Gene: relb / 795414
• ZFINID: ZDB-GENE-030131-9531
• Length: 590
• Species: Danio rerio
• Alignment Length: 527
• Identity: 143/527 - (27%)
• Similarity: 231/527 - (43%)
• Gaps: 113/527 - (21%)

  Fly    50 ELQTDFAN------------LNLPGGNSPHQPPM------ANSPYQNQLLNNGGICQLGATNLIN 96
            :|:.|..|            :.|||   |..||:      .|.|.:|:...|            |
Zfish    15 DLELDLINEYLLEKTNKELTITLPG---PPPPPVDQDIQAVNPPPRNRRTTN------------N 64

  Fly    97 STGVSFGVA--NVTSFGNMYMDHQYFVPAPATVPPSQNFGYHQNGLASDGDIKHVPQ-------- 151
            ...||.|.|  |..||..:...|...:.|..::..::. ...:.||||....:.:||
Zfish    65 PVLVSRGTAPQNSLSFDQVPTAHADGMAAMQSIRGAKG-SSQRRGLASVATQRRIPQQTGTEHLE 128

  Fly   152 -------LRIVEQPVEK-FRFRYKSEMHGTHGSLNGANSKRTPKTFPEVTLCNYDGP------AV 202
                   |.:||||.|: .||||:.|.... ||:.||:|..:.||.|.:.:   .||      .:
Zfish   129 MFLEKPDLVVVEQPKERGMRFRYECEGRSA-GSILGASSTDSNKTLPAIEI---QGPIDNIKKVM 189

  Fly   203 IRCSLFQTNLD-SPHSHQLVVRKDDRDVCDPHDLHVSKERGYVAQFINMGIIHTAKKYIFEELCK 266
            :..||...::. .||.|.||.:.....:|   .:|::........|.|:||....:|.:...|.|
Zfish   190 VTVSLVTKDIPYRPHPHCLVGKDCTDGIC---VIHINPHSNRRHSFANLGIQCVRRKELDASLQK 251

  Fly   267 KKQDRLVFQMNRRELSHKQLQELHQETEREAKDMNLNQVRLCFEAFKIEDNGAWVPLAPPVYSNA 331
            ::              :|.:...:....:..:||::|.|||||:....:.||..:.| .||.||.
Zfish   252 RR--------------NKNIDPFNTGHSKSIEDMDMNVVRLCFQCELEQKNGDRITL-NPVVSNP 301

  Fly   332 INNRKSAQTGELRIVRLSKPTGGVMGNDELILLVEKVSKKNIKVRFFEEDEDGETVWEAYAKFRE 396
            |.::|:..|.||:|.||:...|...|..|:.:|.:||.|.:|::.|..||      |||.|:|.:
Zfish   302 IYDKKATTTAELKINRLNVIRGPCTGKTEIYMLCDKVQKDDIEIIFSIED------WEAKAEFAQ 360

  Fly   397 SDVHHQYAIVCQTPPYKDKDVDREVNVYIELIRPSDDERSFPALPFRYKPRSVI---VSRKRR-R 457
            :|||.|.|||.::||::::|:..|..|.:.|.|.||...|.| :.|.|.|.:..   |:|||: :
Zfish   361 TDVHRQIAIVFKSPPFREQDILEETEVNVCLRRMSDRMDSEP-VKFTYVPDNADPYGVNRKRKMK 424

  Fly   458 TGSSANSSSSGTESSNNSLDLPKTLGLAQP------------------PNG---LPNLSQHDQTI 501
            |....:.|.:..:|.:..::.|.|.....|                  .:|   :|:|:..:...
Zfish   425 TDVKFSESCNIPQSQDLLMNDPGTSQQFDPFYPTPECNVSSAPIAVPLQDGGIQMPSLTVEEMFY 489

  Fly   502 SEEFGRE 508
            :|:|.:|
Zfish   490 NEDFKQE 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rel	NP_477094.1	RHD-n_Relish	150..336	CDD:143644	56/208 (27%)
		IPT_NFkappaB	343..446	CDD:238582	40/102 (39%)
		ANKYR	590..805	CDD:440430
		ANK repeat	640..671	CDD:293786
		ANK repeat	673..708	CDD:293786
relb	XP_021322023.1	RHD-n	134..306	CDD:447596	54/193 (28%)
		RHD_dimer	314..410	CDD:465045	39/102 (38%)