Protein Alignment Rel and dl

DIOPT Version :10

• Sequence 1: NP_477094.1
• Gene: Rel / 41087
• FlyBaseID: FBgn0014018
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: NP_724054.1
• Gene: dl / 35047
• FlyBaseID: FBgn0260632
• Length: 999
• Species: Drosophila melanogaster
• Alignment Length: 683
• Identity: 180/683 - (26%)
• Similarity: 281/683 - (41%)
• Gaps: 150/683 - (21%)

  Fly   129 PSQNFG--------------YHQNGL---------ASDGDIKHVPQLRIVEQPVEK-FRFRYKSE 169
            |:||.|              .:.|||         .|..:::..|.::|.|||..| .||||:.|
  Fly     3 PNQNNGAAPGQGPAVDGQQSLNYNGLPAQQQQQLAQSTKNVRKKPYVKITEQPAGKALRFRYECE 67

  Fly   170 MHGTHGSLNGANSKRTPKTFPEVTLCNYDGPAVIRCSLFQTNLD-SPHSHQLVVRKD-DRDVCDP 232
            .... ||:.|.||....||:|.:.:..|.|.||:..|....:.. .||.|.||.::. .:.||
  Fly    68 GRSA-GSIPGVNSTPENKTYPTIEIVGYKGRAVVVVSCVTKDTPYRPHPHNLVGKEGCKKGVC-- 129

  Fly   233 HDLHVSKERGYVAQFINMGIIHTAKKYIFEELCKKKQDRLVFQMNRRELSHKQLQELHQETEREA 297
             .|.::.|. ..|.|.|:||....||.|  |...|.::.:.....:...||:          .:.
  Fly   130 -TLEINSET-MRAVFSNLGIQCVKKKDI--EAALKAREEIRVDPFKTGFSHR----------FQP 180

  Fly   298 KDMNLNQVRLCFEAF-KIEDNGAWVPLAPPVYSNAINNRKSAQTGELRIVRLSKPTGGVMGNDEL 361
            ..::||.|||||:.| :.|..|.:....|||.|..|.::|:  ..:|.|.||...:..|.||.::
  Fly   181 SSIDLNSVRLCFQVFMESEQKGRFTSPLPPVVSEPIFDKKA--MSDLVICRLCSCSATVFGNTQI 243

  Fly   362 ILLVEKVSKKNIKVRFFEEDEDGETVWEAYAKFRESDVHHQYAIVCQTPPYKDKDVDREVNVYIE 426
            |||.|||:|::|.|||||| ::|::||||:..|:.:|||.|.||..:||.|...|:.....|:|:
  Fly   244 ILLCEKVAKEDISVRFFEE-KNGQSVWEAFGDFQHTDVHKQTAITFKTPRYHTLDITEPAKVFIQ 307

  Fly   427 LIRPSDDERSFPALPFRYKPRSVIVSRK----------RRRTGSSANSSSSGTESSNN------- 474
            |.||||...| .||||.|.|..   |.|          :|:............::...
  Fly   308 LRRPSDGVTS-EALPFEYVPMD---SGKHTFWNLHRHLKRKPDEDLFQQILRLDAKREVQPPTIE 368

  Fly   475 --SLDLPKTLGLAQPPNGL-----------PNLSQHDQTISEEFGREKHL-------NEFIASED 519
              .||.||.....:.|:.:           |.|.|......|::.:|:.|       .:.:..|.
  Fly   369 VIDLDTPKIDVQREIPSEMEFNHEESQQSEPALEQEQSVQQEQYTQEQSLQQEQYTQEQSLQQEQ 433

  Fly   520 FRKLIEHNSS-DLEKICQLDM---------GELQH----------------DGHNRAEVPSHRNR 558
            :.:.:|...| .||:..|.|.         ..:.|                |.|..||....|:.
  Fly   434 YLQQLEQQQSFQLEEPMQQDQELPAQQSFDQAIDHLPDHTSDHIPEDMEAADAHAEAEAHRLRSE 498

  Fly   559 TIKCLDDLF-----EIYKQD---RISPIKI-SHHKVEKWF----IEHALN----NYNRDTLLHEV 606
            ..|.:|.:.     |:.:.|   ::.|..: ::.|:.:|.    ||..::    ....|.|...:
  Fly   499 QEKEIDTIIDEKVRELEQLDLGQQLEPRPLTANDKITEWMKSSEIEQQVHEPSPTAEADVLDSAL 563

  Fly   607 ISHKKDK-LKLAIQTIQVMN--YFNLK---DVVNSTLNADGDSALHVACQQDRAHYIRPLLGMGC 665
            ...|.|| |...::|:..::  |.:.|   |...:|:..:      :|..|.||    ||   ..
  Fly   564 EISKADKTLDELLETVAELDEIYTDFKVQRDTYKNTIQNE------LAGLQGRA----PL---QV 615

  Fly   666 NPNLKNNAGNTPLHVAVKEEHLSCVESFLNGVP 698
            ..:..:.|..|.|.:|.|...|..::..:...|
  Fly   616 EDSFDDAATYTSLQIAFKNPVLIPMDDIMPPTP 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rel	NP_477094.1	RHD-n_Relish	150..336	CDD:143644	60/189 (32%)
		IPT_NFkappaB	343..446	CDD:238582	50/102 (49%)
		ANKYR	590..805	CDD:440430	26/119 (22%)
		ANK repeat	640..671	CDD:293786	6/30 (20%)
		ANK repeat	673..708	CDD:293786	7/26 (27%)
dl	NP_724054.1	RHD-n_Dorsal_Dif	47..220	CDD:143647	60/189 (32%)
		IPT_NFkappaB	225..326	CDD:238582	50/102 (49%)