Protein Alignment Rel and Rela

DIOPT Version :9

• Sequence 1: NP_477094.1
• Gene: Rel / 41087
• FlyBaseID: FBgn0014018
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: XP_006531757.1
• Gene: Rela / 19697
• MGIID: 103290
• Length: 556
• Species: Mus musculus
• Alignment Length: 539
• Identity: 148/539 - (27%)
• Similarity: 217/539 - (40%)
• Gaps: 158/539 - (29%)

  Fly   119 YFVPAPATVPPSQNFGYHQNGLASDGDIKHVPQLRIVEQPVEK-FRFRYKSEMHGTHGSLNGANS 182
            |..|......|:|..|               |.:.|:|||.:: .|||||.|.... ||:.|..|
Mouse    10 YLFPLIFPSEPAQASG---------------PYVEIIEQPKQRGMRFRYKCEGRSA-GSIPGERS 58

  Fly   183 KRTPKTFPEVTLCNYDGPAVIRCSLFQTN-LDSPHSHQLVVRKDDR------DVCDPHDLHVSKE 240
            ..|.||.|.:.:..|.||..:|.||...: ...||.|:| |.||.|      |:|....:|
Mouse    59 TDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHEL-VGKDCRDGYYEADLCPDRSIH---- 118

  Fly   241 RGYVAQFINMGIIHTAKKYIFEELCKKKQDRLVFQMNRRELSHKQLQELHQETEREAKDMNLNQV 305
                 .|.|:||           .|.||:| |...:::|..::.  ...|...|.:..|.:||.|
Mouse   119 -----SFQNLGI-----------QCVKKRD-LEQAISQRIQTNN--NPFHVPIEEQRGDYDLNAV 164

  Fly   306 RLCFEAFKIEDNGAWVPLAPPVYSNAINNRKSAQTGELRIVRLSKPTGGVMGNDELILLVEKVSK 370
            ||||:. .:.|......|..||.|:.|.:.::..|.||:|.|:::.:|..:|.||:.||.:||.|
Mouse   165 RLCFQV-TVRDPAGRPLLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQK 228

  Fly   371 KNIKVRFFEEDEDGETVWEAYAKFRESDVHHQYAIVCQTPPYKDKDVDREVNVYIELIRPSDDER 435
            ::|:|.|....      |||...|.::|||.|.|||.:||||.|..:...|.|.::|.||||.|.
Mouse   229 EDIEVYFTGPG------WEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDREL 287

  Fly   436 SFPALPFRYKPRS---VIVSRKRRRTGSSANS------SSSGTE----------SSNNSLDLPK- 480
            |.| :.|:|.|.:   ..:..||:||..:..|      .:..||          .:.||..:||
Mouse   288 SEP-MEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFNGPTEPRPPTRRIAVPTRNSTSVPKP 351

  Fly   481 -----------------------------------------------------TLGLAQPPNGLP 492
                                                                 .:.|||||...|
Mouse   352 APQPYTFPASLSTINFDEFSPMLLPSGQISNQALALAPSSAPVLAQTMVPSSAMVPLAQPPAPAP 416

  Fly   493 NLS----------------QHDQTISEEFGREKHLNEFIASEDFRKLIEHNS-----SDLEKICQ 536
            .|:                ..:.|:||..   .|| :|.|.||...|:.:::     :||..:..
Mouse   417 VLTPGPPQSLSAPVPKSTQAGEGTLSEAL---LHL-QFDADEDLGALLGNSTDPGVFTDLASVDN 477

  Fly   537 LDMGELQHDG----HNRAE 551
            .:..:|.:.|    |:.||
Mouse   478 SEFQQLLNQGVSMSHSTAE 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rel	NP_477094.1	RHD-n_Relish	150..336	CDD:143644	62/193 (32%)
		IPT_NFkappaB	343..446	CDD:238582	43/102 (42%)
		ANK	638..766	CDD:238125
		ANK repeat	640..671	CDD:293786
		Ank_4	641..691	CDD:290365
		ANK repeat	673..708	CDD:293786
		Ank_2	678..775	CDD:289560
Rela	XP_006531757.1	RHD-n_RelA	26..194	CDD:143645	62/193 (32%)
		IPT_NFkappaB	201..297	CDD:238582	43/102 (42%)
		PHA03247	<262..528	CDD:223021	52/240 (22%)
		DUF5364	<451..539	CDD:375130	11/46 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391433at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24169
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.980