Protein Alignment hyx and CDC73

DIOPT Version :9

• Sequence 1: NP_001163564.1
• Gene: hyx / 41086
• FlyBaseID: FBgn0037657
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_013522.1
• Gene: CDC73 / 851136
• SGDID: S000004410
• Length: 393
• Species: Saccharomyces cerevisiae
• Alignment Length: 551
• Identity: 110/551 - (19%)
• Similarity: 195/551 - (35%)
• Gaps: 190/551 - (34%)

  Fly     1 MADPLSLLRQY------------------NINKKEIVERDSQIIFGEFSWPKSVKTNYLKYGSGK 47
            ||:.|..||::                  :|.|..:||..|.....:.|:|.:.:|.....||
Yeast     1 MANSLDRLREHLKNGDKLVLKNNEGQSTDDITKATMVETLSSDGSTQDSFPLNEETEIEIDGS-- 63

  Fly    48 KGAPREYYTLECLLYLLKNVMLQHSVYVRQCAAEDIPAVNRPDRKELLAYLNGETPTCASIDKSA 112
                  ...|..:::...|.....:.|:..|..:.:..|:...|.:|:.:|:|.|      :.|.
Yeast    64 ------LVQLRIIVHCWMNKDSSAADYLADCQNKQLTNVSFLQRTDLINWLSGNT------ESSQ 116

  Fly   113 PLEIPTQVKRAAEGEPSSVEVAAKKARFEETQVQKVREQLAARWDVNQKETAVNMDNIKSLSETM 177
            .|:.|.|     :||.|.             :|....:.||......:..|:.:::|...:|:.:
Yeast   117 YLKAPGQ-----KGETSD-------------KVDIENKTLAGELSTVKSTTSASLENDSEVSDPV 163

  Fly   178 SVEKIAAIKAKRLANKRTTIKRTDNDEAMGTDLRAILDYDVDSTKDIISRERQWRTRTSILQSTG 242
            .||               |:|..          |.::|::
Yeast   164 VVE---------------TMKHE----------RILVDHN------------------------- 178

  Fly   243 KIFAKNIFAMLQGIKAREEGRNRPQVPNPIKMPEPARIAKPQPQLSQYNRYDQERFNRQKEETEG 307
                    :.|:|.|             ||                        .|....::.|
Yeast   179 --------SALRGAK-------------PI------------------------NFGYLIKDAE- 197

  Fly   308 FKIDTLGTYHGMSLKSVTEGSLAQRKAQANNLPGAPGVIAGAAAGRPKELLPAAQARQLPANGPS 372
                       :.|....:|||...|..    ||..|                |..|....||.|
Yeast   198 -----------LKLVQSIKGSLRGSKLP----PGHKG----------------AHGRISKTNGSS 231

  Fly   373 KRTSRTPIIIIPSANTSLITMLNAKDILQELRFMSTSD-----KKLQGCQRECEVLLQRKRNNQT 432
            ....:.|||:||||.:|::|:.|.|..|.|.::::..:     ..|...::..|      |.::.
Yeast   232 GGPRKDPIILIPSAASSILTVANIKQFLLESKYVNPRNLPSVPNGLVNIEKNFE------RISRP 290

  Fly   433 VSYRVIDNPTKLSQQE-WQRVVAVFVMGPQWQFKGWPWEGNPVDIFSKICAFHLCFSEMKLDSNV 496
            :.:.::||....::.| |.||||:|..|..|||..:.| .:|.::|.:...::..|:...:..:|
Yeast   291 IRFIIVDNTRMFTKPEYWDRVVAIFTTGHTWQFNNYQW-NSPQELFQRCKGYYFHFAGDSVPQHV 354

  Fly   497 ERWSVTLLRLSQNKRHMDRAVLSKFWETLDK 527
            ::|:|..:.|.:|||..|..|:..||.:|:|
Yeast   355 QQWNVEKVELDKNKRFKDVEVVRYFWHSLEK 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hyx	NP_001163564.1	CDC73_N	1..297	CDD:292669	49/313 (16%)
		CDC73_C	376..527	CDD:282965	45/156 (29%)
CDC73	NP_013522.1	CDC73	1..393	CDD:227486	110/551 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345352
Domainoid	1	1.000	86	1.000	Domainoid score	I1874
eggNOG	1	0.900	-	-		E1_COG5157
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004392
OrthoInspector	1	1.000	-	-		otm46825
orthoMCL	1	0.900	-	-		OOG6_102858
Panther	1	1.100	-	-	LDO	PTHR12466
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R183
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.770