Protein Alignment hyx and cdc73

DIOPT Version :10

• Sequence 1: NP_649863.1
• Gene: hyx / 41086
• FlyBaseID: FBgn0037657
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001016031.2
• Gene: cdc73 / 548785
• XenbaseID: XB-GENE-949345
• Length: 531
• Species: Xenopus tropicalis
• Alignment Length: 557
• Identity: 323/557 - (57%)
• Similarity: 398/557 - (71%)
• Gaps: 45/557 - (8%)

  Fly     1 MADPLSLLRQYNINKKEIVERDSQIIFGEFSWPKSVKTNYLKYGSGKKGAPREYYTLECLLYLLK 65
            |||.||:||||||.||||..:..::|||||||||:|||||:.:|:||:|.|||||||:.:|:||.
 Frog     1 MADVLSVLRQYNIQKKEINVKGDEVIFGEFSWPKNVKTNYVIWGTGKEGQPREYYTLDSILFLLN 65

  Fly    66 NVMLQHSVYVRQCAAEDIPAVNRPDRKELLAYLNGETPTCASIDKSAPLEI----PTQVKRAAEG 126
            ||.|.|.||||:.|.|:||.|.|||||:|||||||||.:.||||:||||||    .:||||.|:
 Frog    66 NVHLSHPVYVRRAATENIPVVRRPDRKDLLAYLNGETSSSASIDRSAPLEIGLQRSSQVKRVAD- 129

  Fly   127 EPSSVEVAAKKARFE-ETQVQKVREQLAARWDVNQKETAVNMDNIKSLSETMSVEKIAAIKAKRL 190
               .:...|||.|.| |.:|:..:|:||||.: ..||..|..:.|:||||.||||||||||||.:
 Frog   130 ---EISAEAKKPRIEDEERVRLDKERLAARLE-GHKEGIVATEQIRSLSEAMSVEKIAAIKAKIM 190

  Fly   191 ANKRTTIKRTDNDEAMGTDLRAILDYDVDSTKDIISRERQWRTRTSILQSTGKIFAKNIFAMLQG 255
            |.||:|||...:|:......|:.:|.:||.|:||:||||.|||||:|||||||.|||||||:||.
 Frog   191 AKKRSTIKTDLDDDITALKQRSFVDAEVDFTRDIVSRERVWRTRTTILQSTGKNFAKNIFAILQS 255

  Fly   256 IKAREEGRNRPQVPNPIKMP-EPA-RIAKPQPQLSQYNRYDQERFNRQKEETEGFKIDTLGTYHG 318
            :|||||||...|.|.....| :|| |..||.|  :.||||||||| :.|||||||||||:|||||
 Frog   256 VKAREEGRAPEQRPTQTAAPTDPALRTNKPVP--AAYNRYDQERF-KGKEETEGFKIDTMGTYHG 317

  Fly   319 MSLKSVTEGSLAQRKAQANNLPGAPGVIAGAAAGRPKELLPAAQARQLPANGPSKRTSRTPIIII 383
            |:|||||||:.| ||.|...:...|              .|.:|||. |.|  .|:.||||||||
 Frog   318 MTLKSVTEGASA-RKTQTPAVQPVP--------------RPVSQARP-PPN--QKKGSRTPIIII 364

  Fly   384 PSANTSLITMLNAKDILQELRFMSTSDKKLQGCQRECEVLLQRKRNNQ---------TVSYRVID 439
            |:|.|||||||||||:||:|:|:|:.:||.|||||:.|.|:||:::..         ||.|||:|
 Frog   365 PAATTSLITMLNAKDLLQDLKFVSSEEKKKQGCQRDNETLIQRRKDQMQPGGTTISVTVPYRVVD 429

  Fly   440 NPTKLSQQEWQRVVAVFVMGPQWQFKGWPW---EGNPVDIFSKICAFHLCFSEMKLDSNVERWSV 501
            .|.||..|:|.|||||||.||.||||||||   :|:|||||:||..|||.:.|::||.||::|.|
 Frog   430 QPLKLLPQDWDRVVAVFVQGPAWQFKGWPWVLPDGSPVDIFAKIKGFHLKYDEVRLDPNVQKWDV 494

  Fly   502 TLLRLSQNKRHMDRAVLSKFWETLDKYIAKYKPDLRY 538
            |||.||.:|||:||.|..|||||||:|:.|.|..||:
 Frog   495 TLLELSYHKRHLDRPVFLKFWETLDRYMVKNKSHLRF 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hyx	NP_649863.1	CDC73_N	1..297	CDD:464994	178/302 (59%)
		CDC73_C	376..527	CDD:461570	100/162 (62%)
cdc73	NP_001016031.2	CDC73_N	1..297	CDD:464994	178/302 (59%)
		CDC73_C	357..520	CDD:461570	100/162 (62%)