Protein Alignment neur and Neurl1

DIOPT Version :10

• Sequence 1: NP_476652.1
• Gene: neur / 41085
• FlyBaseID: FBgn0002932
• Length: 754
• Species: Drosophila melanogaster
• Sequence 2: NP_001388553.1
• Gene: Neurl1 / 309459
• RGDID: 1307021
• Length: 574
• Species: Rattus norvegicus
• Alignment Length: 677
• Identity: 187/677 - (27%)
• Similarity: 288/677 - (42%)
• Gaps: 176/677 - (25%)

  Fly    98 CP---GPNNLP--PLQFH-SVHGDNIRISRDGTLARRFESFCRAITFSARPVRINERICVKFAEI 156
            ||   ....||  ||.|| ...|..|.:.......:|..|||.|||||.|||.|.|::.:|..:.
  Rat    49 CPPALSGGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKK 113

  Fly   157 SNNWNGGIRFGFTSNDPVTLE-GTLPKYACPDLTNRPGFWAKALHEQYCEKDNILYYYVNGAGDV 220
            ...|:|.:|.||||.||..:. .:|||||||||.::.|||||||.|::..:.||:.::|:..|.|
  Rat   114 QCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRV 178

  Fly   221 IYGINNEEKGVILTGIDTRSLLWTVIDIYGNCTGIEFLDSRIYMYQQQPAAIPMATVPAQQQQMP 285
            .|.||.....:..:|:.|...||.::|:||...|::.|||.:        .:|....|.....:.
  Rat   179 FYRINESAAMLFFSGVRTADPLWALVDVYGLTRGVQLLDSEL--------VLPDCLRPRSFTALR 235

  Fly   286 QPAANASSALNSHHPHQQSRRSLPGHTAAIEHDLERHVMPSLQSLHLAGNGGSVASVEQAAIAHD 350
            :|:....:        .::|.|:                 ||..|::.|..|.
  Rat   236 RPSLRCEA--------DEARLSV-----------------SLCDLNVPGADGE------------ 263

  Fly   351 LANGLP----PLRYNA----NGRLIP------VPFHNTK-GRNVRLSQDRFVASRTESDFCQGYV 400
              :|.|    |:..|:    :.|.:|      :.||..: |.:||:..::.||........:..|
  Rat   264 --DGAPPAGCPIPQNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVARLEHGRDERALV 326

  Fly   401 FTARPIRIGEKLIVQVLKTEQMYVGALALGLTSCNPAMLQPNDLPNDSDFLLDRPEYWVVSKDIA 465
            ||:||:|:.|.:.::|.::.....|||:.|:|:|:|..|:|.|||...:.|:||.|:|.|.: :.
  Rat   327 FTSRPVRVAETIFIKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCR-VP 390

  Fly   466 AAPQRGDEIAFFVAPNGEVSISKNNGPAVVVMHVDQSLQLWAFLDVYGSTQSLRMFRQQLPNMVA 530
            .....||.:...|..:||:.:|.|..||.:.:.||.|..||....::|:...:|:....:.....
  Rat   391 GPLHSGDILGLVVNADGELHLSHNGAPAGMQLCVDASQPLWMLFSLHGAITQVRILGSTIMAERG 455

  Fly   531 YPSQPQVNVNASSSSACNAASTSRMLPMTESMSSLNAGATAKLLHHPSQLSVAQSTSTLASAGGV 595
            .||.|           |:.|||    |.:                 ||.|
  Rat   456 GPSLP-----------CSPAST----PTS-----------------PSAL--------------- 473

  Fly   596 NGSRMISMPSNGDILQIQPNGGGTVLVVNLPPASSSHDINGQLAARPTATVTSSGVLAGACSSGT 660
             |||:                                       :.|..:...||.|.|  |:|.
  Rat   474 -GSRL---------------------------------------SDPLLSTCGSGPLGG--SAGG 496

  Fly   661 LISTTSSQYIEQPIANSTNNAANKWKDSLSDQQSTDSSAECTICYENPIDSVLYMCGHMCMCYDC 725
            ....:.....|.|:    .....:|.|            |||||||:.:|:|:|.|||||:||.|
  Rat   497 TAPNSPVSLPESPV----TPGLGQWSD------------ECTICYEHAVDTVIYTCGHMCLCYSC 545

  Fly   726 AIEQWRGVGGGQCPLCRAVIRDVIRTY 752
            .:...:.: ...||:||..|:|:|:||
  Rat   546 GLRLKKAL-HACCPICRRPIKDIIKTY 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neur	NP_476652.1	Neuralized	109..259	CDD:462112	61/151 (40%)
		Neuralized	371..520	CDD:462112	48/149 (32%)
		mRING-HC-C3HC5_NEU1	698..752	CDD:438309	25/53 (47%)
Neurl1	NP_001388553.1	NEUZ	61..183	CDD:128856	53/121 (44%)
		Neuralized	296..447	CDD:462112	49/151 (32%)
		mRING-HC-C3HC5_NEU1A	515..573	CDD:438439	29/70 (41%)