Protein Alignment neur and Neurl1b

DIOPT Version :10

• Sequence 1: NP_476652.1
• Gene: neur / 41085
• FlyBaseID: FBgn0002932
• Length: 754
• Species: Drosophila melanogaster
• Sequence 2: NP_001075125.1
• Gene: Neurl1b / 240055
• MGIID: 3643092
• Length: 546
• Species: Mus musculus
• Alignment Length: 682
• Identity: 184/682 - (26%)
• Similarity: 288/682 - (42%)
• Gaps: 174/682 - (25%)

  Fly    90 LVRRSPSSCPGPNNLPPL----QFHS-VHGDNIRISRDGTLARRFESFCRAITFSARPVRINERI 149
            |:...|...|||.....|    :||: ..|.|:|:......|.|..|||..:||:.||:|:.|::
Mouse    18 LLATRPCYGPGPERRAVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQV 82

  Fly   150 CVKFAEISNNWNGGIRFGFTSNDPVTLEG-TLPKYACPDLTNRPGFWAKALHEQYCEKDNILYYY 213
            .::...:...|:|.:|||||::||..:.. .:||||||||..|||:|||||.|....:|.:|.|:
Mouse    83 RLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYW 147

  Fly   214 VNGAGDVIYGINNEEKGVILTGIDTRSLLWTVIDIYGNCTGIEFLDSRIYMYQQQPAAIPMATVP 278
            .:..|.|.|.:|:.|..:...|:.....||.:||:||....::.|:|..     .....|:....
Mouse   148 ADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLESTF-----ADTLTPLRLGQ 207

  Fly   279 AQQQQMPQPAANASSALNSHHPHQQSRRSLPGHTAAIEHDLERHVMPSLQSLHLAGNGGSVASVE 343
            |:....|.|.::.::..::                   ::||.:.:
Mouse   208 ARLSACPPPGSHDAANFDN-------------------NELENNQV------------------- 234

  Fly   344 QAAIAHDLANGLPPLRYNANGRLIPVP------------FHNTKGRNVRLSQDRFVASRTESDFC 396
            .|.:.| ||.|.|........|..|.|            ||.|:|.:|.||.||.:|.....|..
Mouse   235 VAKLGH-LALGRPDAAVPCVARERPRPASSPALLDAELRFHATRGPDVSLSADRRLACAPRPDGG 298

  Fly   397 QGYVFTARPIRIGEKLIVQVLKTEQMYVGALALGLTSCNPAMLQPNDLPNDSDFLLDRPEYWVVS 461
            :..||:.||:|.||.|.|:|.:.......|:|.|:|||:|..|:|::||.|...||||.|||||:
Mouse   299 RTLVFSERPLRPGESLCVEVGRPGLAAPAAVAFGITSCDPGALRPSELPADPAALLDRKEYWVVA 363

  Fly   462 KDIAAAPQRGDEIAFFVAPNGEVSISKNNGPAVVVMHVDQSLQLWAFLDVYGSTQSLRMFRQQLP 526
            : ....|..||.::|.:.|.|:|.::.|..|...::.||.|..||||..|.|
Mouse   364 R-AGPVPSGGDALSFTLRPGGDVLLAVNGRPRGRLLCVDTSQALWAFFAVRG------------- 414

  Fly   527 NMVAYPSQPQVNVNASSSSACNAASTSRMLPMTESMSSLNAGATAKLLHHPSQLSVAQSTSTLAS 591
                                 ..|...|:|...:|                       |:.|:..
Mouse   415 ---------------------GVAGQLRLLGTLQS-----------------------SSETMTP 435

  Fly   592 AGGVNGSRMISMPSNGDILQIQPNGGGTVLVVNLPPASSSHDINGQLAARPTATVTSSGVLAGAC 656
            :|..:||:                            ..|..|:             :.||...:.
Mouse   436 SGSFSGSQ----------------------------DDSDSDM-------------TFGVNQSSS 459

  Fly   657 SSGTLISTTSSQYIEQPIANSTNNAANKWKDSLSDQQSTDS-SAECTICYENPIDSVLYMCGHMC 720
            :|.:.:.|..|..:..|::           .:.|..:.|.| :.|||:|:::.:|:|:|.|||||
Mouse   460 ASESSLVTAPSSPLSPPVS-----------PAFSAPEPTGSRNGECTVCFDSEVDTVIYTCGHMC 513

  Fly   721 MCYDCAIEQWRGVGGGQCPLCRAVIRDVIRTY 752
            :|:.|.: :.|......||:||..|:|||:.|
Mouse   514 LCHGCGL-RLRRQARACCPICRRPIKDVIKIY 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neur	NP_476652.1	Neuralized	109..259	CDD:462112	57/151 (38%)
		Neuralized	371..520	CDD:462112	60/148 (41%)
		mRING-HC-C3HC5_NEU1	698..752	CDD:438309	23/53 (43%)
Neurl1b	NP_001075125.1	Neuralized	41..192	CDD:462112	57/150 (38%)
		Neuralized	273..424	CDD:462112	62/185 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	429..490		15/112 (13%)
		mRING-HC-C3HC5_NEU1B	490..546	CDD:438440	24/56 (43%)