Protein Alignment neur and Neurl4

DIOPT Version :10

• Sequence 1: NP_476652.1
• Gene: neur / 41085
• FlyBaseID: FBgn0002932
• Length: 754
• Species: Drosophila melanogaster
• Sequence 2: XP_061511101.1
• Gene: Neurl4 / 1280706
• VectorBaseID: AGAMI1_013643
• Length: 1891
• Species: Anopheles gambiae
• Alignment Length: 774
• Identity: 150/774 - (19%)
• Similarity: 272/774 - (35%)
• Gaps: 247/774 - (31%)

  Fly    96 SSCPGPNNLPPLQFHSVHGDNIRISRDGTLARR---FESFCRAITFSARPVRINERICVKFAEIS 157
            ||...|::  .|:||:..|..:::|.:...|.|   .:.|...:..:.||:..||...::...:.
Mosquito   240 SSVSDPSD--KLRFHTRCGSLVKLSANCRTAERRRPLDEFNNGVVMTHRPLWDNELFEIRIDRLV 302

  Fly   158 NNWNGGIRFGFTSNDPVTLE----------GTLPKYACPDLTNRPGF---WAKALHEQYCEKDNI 209
            :.|:|.|..|.|::.|..|:          ||:....|..|||..|.   :.:...::..|.|.:
Mosquito   303 DKWSGSIEVGVTTHCPSALQFPATMTNLRSGTIMMSGCGILTNGKGTRREYGEFNLDELREGDRV 367

  Fly   210 ---------LYYYVNGAGDVIYGINNEEKGVILTGIDTRSLLWTVIDIYGNCTGIEFLDSRIYMY 265
                     |:||:||          .::||..|.:  ...||.|||:||....:..:|..   .
Mosquito   368 GMMRKANGNLHYYING----------RDQGVAATRV--AQTLWGVIDLYGMTIKVTIVDRD---E 417

  Fly   266 QQQPAAIP----MATVPAQQQQMPQPAANASSALNSHHPHQQSRRSLPGHTAAIEHDLERHVMPS 326
            ::|...:.    :.::||..|::|...|.
Mosquito   418 REQRNLVTRRNHLLSMPATVQELPLGVAG------------------------------------ 446

  Fly   327 LQSLHLAGNGGSVASVEQAAIAHDLANGLP-PLRYNANGR----LIPVPFHNTKGRNVRLSQDRF 386
                 :|.:|| :|:|.          |.| ...|...|.    |..:.||.|.|.:..::....
Mosquito   447 -----MATHGG-IATVA----------GTPSEAEYVGAGSTALLLDRLTFHPTCGSHASVTHSGR 495

  Fly   387 VASR--TESDFCQGYVFTARPIRIGEKLIVQVLKTEQMYVGALALGLTSCNPAMLQPNDLPNDSD 449
            .|.|  ...||..|.|.|.||:|..|...|::.:....:.|::.:|:|:.:|..|   |.|
Mosquito   496 TALRPNASDDFNNGVVLTRRPLRPNELFQVRLERVVTKWAGSIEMGVTTHSPTEL---DFP---- 553

  Fly   450 FLLD--RPEYW------VVSKDIAAAPQRGDEIAFFVAPNGEVSISKNNGPAVVVMH-----VDQ 501
            |.:.  |...|      |:...:....|.|..:......:....:.|::|    .:|     :||
Mosquito   554 FTMTNVRTGTWMMTGNGVMHNGMTVIEQYGQNLDRLQVGDRVGVVRKDDG----TLHFWVNGIDQ 614

  Fly   502 S-------LQLWAFLDVYGSTQSLRMF-----------RQQLPNMVAYPS-QPQVNVNA------ 541
            .       .:::..:|:||......:.           ...:.|...:|| :|::..|.
Mosquito   615 GPAATGVPEKVYGVIDLYGQAAQASIVDTSECGTPDTGNSTISNTTLFPSAEPRMRFNTCVHGRN 679

  Fly   542 -----SSSSACNAAS----------TSRMLPMTESM------------SSLNAGATAKLLHHPSQ 579
                 ...:||...:          :||.|...|..            .|:..|.||.   .|.:
Mosquito   680 AHIINGGLTACRPKALAEFNDAIVFSSRPLRQRELFEIALDTVVDRWNGSIEIGVTAM---RPDE 741

  Fly   580 LSVAQSTS-----TLASAGGV--------------------NGSRMISMPSNGDILQIQPNG--G 617
            ||:..:.:     |:..:|..                    .||| :.:..|||.:....||  .
Mosquito   742 LSLPSTATDLEHDTIMVSGTTLLLNGCTVRSDLPFDLDALGQGSR-VGVMRNGDAIHFLVNGIDL 805

  Fly   618 GTVLVVNLPPASSSHDINGQLAARPTATVTSSGVLAGACS--SGTLIS------------TTSSQ 668
            |.......|...:..|:.|| .|:.:.|..:....||||:  :|:::.            :.:||
Mosquito   806 GAFYDSKAPNLYAVVDLYGQ-CAQVSITAPTHAPGAGACAGVAGSVVGPNGGDLRAPYAISENSQ 869

  Fly   669 YIE-----QPI-------------ANSTNNAANKWKDSLSDQQSTDSSAECTICYENPI 709
            .::     ||:             |::|....:.|  :|:.:.:..:.:.|.:..:.|:
Mosquito   870 SLQATSVIQPMALVESKHRWSCISASNTVTLGHNW--TLATRGTNAALSHCLVFSDRPL 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neur	NP_476652.1	Neuralized	109..259	CDD:462112	42/174 (24%)
		Neuralized	371..520	CDD:462112	37/170 (22%)
		mRING-HC-C3HC5_NEU1	698..752	CDD:438309	2/12 (17%)
Neurl4	XP_061511101.1	None