Protein Alignment neur and neurl1

DIOPT Version :10

• Sequence 1: NP_476652.1
• Gene: neur / 41085
• FlyBaseID: FBgn0002932
• Length: 754
• Species: Drosophila melanogaster
• Sequence 2: NP_001090706.1
• Gene: neurl1 / 100036686
• XenbaseID: XB-GENE-954449
• Length: 555
• Species: Xenopus tropicalis
• Alignment Length: 668
• Identity: 184/668 - (27%)
• Similarity: 289/668 - (43%)
• Gaps: 177/668 - (26%)

  Fly   104 LPPLQFH-SVHGDNIRISRDGTLARRFESFCRAITFSARPVRINERICVKFAEISNNWNGGIRFG 167
            :.||.|| ...|..|.:.......:|..|||.|||||.|||.|:|::.:|..:....|:|.:|.|
 Frog    43 ITPLLFHPHAKGSQIIMDTSQKAVKRQASFCNAITFSNRPVVIHEQVRLKITKKQCCWSGALRLG 107

  Fly   168 FTSNDPVTLE-GTLPKYACPDLTNRPGFWAKALHEQYCEKDNILYYYVNGAGDVIYGINNEEKGV 231
            |||.||..:. .||||||||||.::.|||||||.|::..:.||:.::|:..|.|.|.:|:....:
 Frog   108 FTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDFGSML 172

  Fly   232 ILTGIDTRSLLWTVIDIYGNCTGIEFLDSRIYMYQQQPAAIPMATVPAQQQQMPQPAANASSA-- 294
            ..:|:.....||.:||:||...|:|.|||.|..        |..:.|.....:|:|:....:.
 Frog   173 FFSGVRITEPLWALIDVYGLTRGVELLDSEIIP--------PDCSRPRSFTSIPRPSLRRETEDT 229

  Fly   295 --------LNSHHPHQQSRRS---LPGHTAAIEHDLERHVMPS-LQSLHLAGNGGSVASVEQAAI 347
                    ||....:.|:..:   :|.::...:|.   |::|| |:|
 Frog   230 RLSVSLCDLNLQEDNYQTMTTMCPIPQNSLNSQHS---HLLPSQLES------------------ 273

  Fly   348 AHDLANGLPPLRYNANGRLIPVPFHNTKGRNVRLSQDRFVASRTESDFCQGYVFTARPIRIGEKL 412
              ||.                  ||..:|.:::...|:.||....:...:..|||.||:||.|.:
 Frog   274 --DLR------------------FHQLRGAHIKTLDDQTVARLEHAREERTLVFTNRPLRINETI 318

  Fly   413 IVQVLKTEQMYVGALALGLTSCNPAMLQPNDLPNDSDFLLDRPEYWVVSKDIAAAPQRGDEIAFF 477
            .|::.|:.....|.|:.|:|||:|:.|:|:|||.:.:.|:||.|:|.|.: :....|.||.:.|.
 Frog   319 FVKINKSNSSRSGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCR-VLVPLQSGDILGFV 382

  Fly   478 VAPNGEVSISKNNGPAVVVMHVDQSLQLWAFLDVYGSTQSLRMFRQQLP---NMVAYPSQPQVNV 539
            :...||:.:|.|.....:.:.||.|..||.|..::|:...:|:....:.   ...:.||.|....
 Frog   383 INGEGELHLSHNGTSTGMQVCVDCSQPLWMFFGLHGTIMQIRILGSTISTDNREASAPSSPTSAP 447

  Fly   540 NASSSSACNAASTSRMLPMTESMSSLNAGATAKLLHHPSQLSVAQSTSTLASAGGVNGSRMISMP 604
            | |.::.|:|.|.    |:..|..|...|         |.:::....|.            :|||
 Frog   448 N-SPTAPCSAISD----PILNSCVSAPMG---------SSINITAPNSP------------VSMP 486

  Fly   605 SNGDILQIQPNGGGTVLVVNLPPASSSHDINGQLAARPTATVTSSGVLAGACSSGTLISTTSSQY 669
                                                                             
 Frog   487 ----------------------------------------------------------------- 486

  Fly   670 IEQPIANSTNNAANKWKDSLSDQQSTDSSAECTICYENPIDSVLYMCGHMCMCYDCAIEQWRGVG 734
             |.|::.|.:.:   |.|            ||||||||.:|:|:|.|||||:||.|.: :.:.:.
 Frog   487 -ESPLSPSLSGS---WSD------------ECTICYENLVDTVIYSCGHMCLCYTCGL-KLKKMN 534

  Fly   735 GGQCPLCRAVIRDVIRTY 752
            ...||:||.:|:|:|:||
 Frog   535 NACCPICRRLIKDIIKTY 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neur	NP_476652.1	Neuralized	109..259	CDD:462112	62/151 (41%)
		Neuralized	371..520	CDD:462112	49/148 (33%)
		mRING-HC-C3HC5_NEU1	698..752	CDD:438309	26/53 (49%)
neurl1	NP_001090706.1	NEUZ	44..166	CDD:128856	54/121 (45%)
		Neuralized	277..427	CDD:462112	50/150 (33%)
		RING_Ubox	498..554	CDD:473075	30/68 (44%)