Protein Alignment tgo and arnt2

DIOPT Version :10

• Sequence 1: NP_731308.1
• Gene: tgo / 41084
• FlyBaseID: FBgn0264075
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_009301213.1
• Gene: arnt2 / 64277
• ZFINID: ZDB-GENE-001207-3
• Length: 738
• Species: Danio rerio
• Alignment Length: 716
• Identity: 328/716 - (45%)
• Similarity: 420/716 - (58%)
• Gaps: 135/716 - (18%)

  Fly     8 DKERFASRENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVAHMKALRGTGNT 72
            ||||:| ||||.|||||||||||.|||||||||||||||||||||||||||||:|||::||||||
Zfish    74 DKERYA-RENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNT 137

  Fly    73 SSDGTYKPSFLTDQELKHLILEAADGFLFVVSCDSGRVIYVSDSVTPVLNYTQSDWYGTSLYEHI 137
            |:||.|||||||:||||||||||||||||||:.::|||||||||||||||:.||:|:|::|:|.:
Zfish   138 STDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNHPQSEWFGSTLFEQV 202

  Fly   138 HPDDREKIREQLSTQESQNAGRILDLKSGTVKKEGHQSSMRLSMGARRGFICRMRVGNVNPESMV 202
            ||||.:|:||||||.|:...|||||||:|||||||.|||||:.||:||.||||||.|:. |...:
Zfish   203 HPDDVDKLREQLSTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGSA-PLDHI 266

  Fly   203 SGHLNRL-----KQRNSLGPSRDG-TNYAVVHCTGYIKNWPPTDM-FPNMHMERDVDDMSSHCCL 260
            |  ||||     :.||.||||::| ..|:|||||||||.|||..| .|:...|.   ..:|..||
Zfish   267 S--LNRLSSMRKRYRNGLGPSKEGEAQYSVVHCTGYIKAWPPAGMTIPDEDTEA---GQTSKYCL 326

  Fly   261 VAIGRLQVTSTAAN-DMSGSNNQSEFITRHAMDGKFTFVDQRVLNILGYTPTELLGKICYDFFHP 324
            ||||||||||:..: ||:|.:..:||::||..||..||||.|.:|::||.|.:||||...:|.||
Zfish   327 VAIGRLQVTSSPVSMDMNGLSVPTEFLSRHNSDGIITFVDPRCINVIGYQPQDLLGKDILEFCHP 391

  Fly   325 EDQSHMKESFDQVLKQKGQMFSLLYRARAKNSEYVWLRTQAYAFLNPYTDEVEYIVCTNSSGKTM 389
            |||||::|||.||:|.|||:.|::||.|.||.|::.:||.::.|.|||:||:|||:|||::.|
Zfish   392 EDQSHLRESFQQVVKLKGQVLSVMYRFRMKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVK-- 454

  Fly   390 HGAPLDAAAAHTPEQVQQQQQQEQHVYVQAAPGVDYARRELTPVGSATNDGMYQ-------THML 447
                          |:|||||.|..|:.:  .|:........|| |..:.|:::       |..|
Zfish   455 --------------QLQQQQQAELEVHQR--DGLTAYDLSQVPV-SGVSAGVHESGKSIDKTESL 502

  Fly   448 AMQAPTPQ---------QQQQQQQRPGSAQTTPVGYTYDTTHSPYSAGG-----PSPLAKIP--- 495
            ..|...|:         ..:::...|.|   |..|....:..||:..|.     .|.:..:|
Zfish   503 FSQERDPRFSDIYTGISTSEKKMMVPSS---TSGGQQLYSQGSPFQPGHSGKSFSSSVIHVPGVN 564

  Fly   496 -------KSGTSPTPVAPN------SWAALRPQQQQQQQQP------------VTEGYQYQQ--- 532
                   .:|.:.:.::..      ||:..||....|||.|            :...:.||.
Zfish   565 DIQSTAGSAGQNLSQISRQINTGQVSWSGNRPPFSGQQQIPAQSNKAQSSPFGIGSSHSYQADPS 629

  Fly   533 -----TSPA-RSPSGPTYTQLSAGNG----NRQQAQPGAYQAGPPPPPNAPGMW-DWQ-----QA 581
                 :||| .||||..|:.|:..|.    :.:.:|.|....|.|..     :| .||     |.
Zfish   630 SYSPLSSPATSSPSGNAYSNLANRNTAFDVSGESSQSGGQFQGRPSE-----VWSQWQSQHHSQQ 689

  Fly   582 GGHPHPPHPTAHPHHPHAHPGGPAGAGQPQGQEFSDMLQML-DHTPTT----FEDL-NINMFSTP 640
            .|.|||        |..|          .|.:.|.|||.|. |.|..|    .||. ::.|| .|
Zfish   690 AGDPHP--------HTQA----------SQTEVFQDMLPMPGDPTQGTTNYNIEDFADLGMF-PP 735

  Fly   641 F 641
            |
Zfish   736 F 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tgo	NP_731308.1	bHLH-PAS_ARNT	9..74	CDD:381517	57/64 (89%)
		PAS	90..154	CDD:214512	46/63 (73%)
		PAS_11	282..384	CDD:464214	56/101 (55%)
arnt2	XP_009301213.1	bHLH-PAS_ARNT	75..139	CDD:381517	57/64 (89%)
		PAS	152..258	CDD:395786	78/105 (74%)
		PAS_11	351..451	CDD:464214	56/99 (57%)