Protein Alignment tgo and arnt

DIOPT Version :10

• Sequence 1: NP_731308.1
• Gene: tgo / 41084
• FlyBaseID: FBgn0264075
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001428910.1
• Gene: arnt / 493634
• ZFINID: ZDB-GENE-060126-7
• Length: 747
• Species: Danio rerio
• Alignment Length: 713
• Identity: 310/713 - (43%)
• Similarity: 394/713 - (55%)
• Gaps: 126/713 - (17%)

  Fly     2 DEANIQDKERFASRENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVAHMKAL 66
            |.....|||||| ||||.||||||||||||||||||||||.||||||||||||||||||:|||:|
Zfish    53 DGGGSNDKERFA-RENHSEIERRRRNKMTAYITELSDMVPACSALARKPDKLTILRMAVSHMKSL 116

  Fly    67 RGTGNTSSDGTYKPSFLTDQELKHLILEAADGFLFVVSCDSGRVIYVSDSVTPVLNYTQSDWYGT 131
            |||||||:|||||||||||||||||||||||||||||||::|||:|||||||||||..||||.|:
Zfish   117 RGTGNTSTDGTYKPSFLTDQELKHLILEAADGFLFVVSCETGRVVYVSDSVTPVLNQAQSDWLGS 181

  Fly   132 SLYEHIHPDDREKIREQLSTQE-SQNAGRILDLKSGTVKKEGHQSSMRLSMGARRGFICRMRVGN 195
            |||:.:||||.||:||||||.| :.|:||:||:|:|||||||.|:::|:||||||.||||||.|
Zfish   182 SLYDQLHPDDVEKLREQLSTTENNNNSGRMLDMKTGTVKKEGGQATVRMSMGARRSFICRMRCG- 245

  Fly   196 VNPESMVSGHLNRL-----KQRNSLGPSRDG-TNYAVVHCTGYIKNWPPTDMFPNMHMERDVDDM 254
            |.|...||  ||||     :.||.||.::|| ..|.||||||||::|||..|  |:..|...::.
Zfish   246 VCPVEPVS--LNRLNFLRTRNRNGLGSAKDGEQQYVVVHCTGYIRSWPPAGM--NLSEEEADNNQ 306

  Fly   255 SSHCCLVAIGRLQVTSTAANDMSGSNNQS---EFITRHAMDGKFTFVDQRVLNILGYTPTELLGK 316
            .:..|||||||||||...::  :..||.|   |||:||...|.:||||.|....:|:...|||||
Zfish   307 GNRFCLVAIGRLQVTCCPSD--TSINNISVPVEFISRHNSQGVYTFVDHRCTATVGFQTQELLGK 369

  Fly   317 ICYDFFHPEDQSHMKESFDQVLKQKGQMFSLLYRARAKNSEYVWLRTQAYAFLNPYTDEVEYIVC 381
            ...||.|||||..:::|..||:|.:||:.|:::|.::|:.|:||:||.::.|.||:::|:|||:|
Zfish   370 NILDFAHPEDQGLLRDSLQQVVKLRGQVMSVMFRFQSKSREWVWMRTSSFTFQNPFSEEIEYIIC 434

  Fly   382 TNS--------------SGKTMHGAPLDAAAAHTPEQVQQQQQQEQHVYVQAAPGVDYARRELTP 432
            ||:              |..::..:| :..:..:|..|..:|.|:|.|             ||..
Zfish   435 TNTNVNRGSSEGSVSPLSSPSLGQSP-NCPSTPSPGCVTVRQLQQQQV-------------ELDG 485

  Fly   433 VGSATNDGMYQTHMLAMQAPTPQQQQQQQQRPGSAQTTPVGYTYDTTHSPYSAGGPSPLAKIPKS 497
            .|              |...||.:..|......|.||..| .:.|.:....|:...|.....|.:
Zfish   486 GG--------------MSQETPYENSQVALPQVSVQTCGV-VSADHSSKAVSSSVSSGQQVYPPA 535

  Fly   498 GTSPTPVAPNSW--AALRPQQQ------------QQQQQPVTEGYQYQQTSPARSPSGPT----- 543
            ...|:|..|...  :.:.|||.            |..:|....|......||.::|||||
Zfish   536 AAFPSPARPTETFRSPVLPQQMVPVAHSAGQMLAQMSRQSTPSGVSGSNNSPIQAPSGPTAPPGL 600

  Fly   544 --------YTQLSAGNGNRQQAQP----GAYQAGPPPPPNAPGMW-----------DWQQAGGHP 585
                    .||..||...:.|:.|    |...|..|...::.|..           .:||...|.
Zfish   601 WNTTRQPFSTQQVAGPIGKNQSAPFNMGGFSSASAPSTSSSFGQMGGASASMASTSSYQQINSHS 665

  Fly   586 HP----------------PHPT-------AHPHHPHAHPGGPAGAGQPQGQEFSDMLQMLDHT 625
            :|                ..|.       ..|...|............|...|.|:|.|||.:
Zfish   666 NPSTNGYGDVGQIAAAFGTRPAEGVTGWQQWPSQTHTQASADTQVQNNQTDMFPDVLSMLDQS 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tgo	NP_731308.1	bHLH-PAS_ARNT	9..74	CDD:381517	59/64 (92%)
		PAS	90..154	CDD:214512	51/64 (80%)
		PAS_11	282..384	CDD:464214	48/104 (46%)
arnt	NP_001428910.1	None