Protein Alignment tgo and Clk

DIOPT Version :10

• Sequence 1: NP_731308.1
• Gene: tgo / 41084
• FlyBaseID: FBgn0264075
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001014576.1
• Gene: Clk / 38872
• FlyBaseID: FBgn0023076
• Length: 1027
• Species: Drosophila melanogaster
• Alignment Length: 750
• Identity: 174/750 - (23%)
• Similarity: 284/750 - (37%)
• Gaps: 211/750 - (28%)

  Fly     2 DEANIQDKER-FASRENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVAHMKA 65
            ||::.:|..: |..|::....|::||::..:.:.:||.::.|.|   ||.||.|:|:..:|.:|
  Fly     3 DESDDKDDTKSFLCRKSRNLSEKKRRDQFNSLVNDLSALISTSS---RKMDKSTVLKSTIAFLK- 63

  Fly    66 LRGTGNTSSDGT--------YKPSFLTDQELKHLILEAADGFLFVVSCDSGRVIYVSDSVTPVLN 122
               ..|.::|.:        :||:||::.|..||:||:.|||:.|.| ..|.:.|.|:|:|..|.
  Fly    64 ---NHNEATDRSKVFEIQQDWKPAFLSNDEYTHLMLESLDGFMMVFS-SMGSIFYASESITSQLG 124

  Fly   123 YTQSDWYGTSLYEHIHPDDREKIREQLSTQESQNAGRILDLKSGTVKKEGHQSSMRLSMGARRGF 187
            |...|.|..::|:..:..|.|.:....     .|...:::.:...:     .||.:::      |
  Fly   125 YLPQDLYNMTIYDLAYEMDHEALLNIF-----MNPTPVIEPRQTDI-----SSSNQIT------F 173

  Fly   188 ICRMRVGNVNPESMVSGHLNRLKQRNSLGPSRDGTNYAVVHCTGYIKNWPPTD------------ 240
            ...:|.|.:.                    ..|...|.:|...||.:|...|.
  Fly   174 YTHLRRGGME--------------------KVDANAYELVKFVGYFRNDTNTSTGSSSEVSNGSN 218

  Fly   241 ----MFPNMHMERDVDDMSSHCCLVAIGRLQVTSTAANDMSGSN-NQSEFITRHAMDGKFTFVDQ 300
                :.|.:..:....::......|..||:| ......:||..: ..:||.::|:|:.||.|:|.
  Fly   219 GQPAVLPRIFQQNPNAEVDKKLVFVGTGRVQ-NPQLIREMSIIDPTSNEFTSKHSMEWKFLFLDH 282

  Fly   301 RVLNILGYTPTELLGKICYDFFHPEDQSHMKESFDQVLKQKGQMFSLLYRARAKNSEYVWLRTQA 365
            |...|:||.|.|:||...||::|.:|...:....:: |:|.|:..|..||...|..:::||:|..
  Fly   283 RAPPIIGYMPFEVLGTSGYDYYHFDDLDSIVACHEE-LRQTGEGKSCYYRFLTKGQQWIWLQTDY 346

  Fly   366 YAFLNPYTDEVEYIVCT---------------------NSSGKTMHG----------APLDAAAA 399
            |...:.:..:.:|:|||                     ||:..|.:|          :...|:|.
  Fly   347 YVSYHQFNSKPDYVVCTHKVVSYAEVLKDSRKEGQKSGNSNSITNNGSSKVIASTGTSSKSASAT 411

  Fly   400 HTPEQVQQQQQQEQHVYV---QAAPGVDYARRELTPVGSATNDGMYQTHMLAMQAPTPQQQQQQQ 461
            .|....:...|......:   .|:.|.:.|         ||:..:..:.|.:..|..|.
  Fly   412 TTLRDFELSSQNLDSTLLGNSLASLGTETA---------ATSPAVDSSPMWSASAVQPS------ 461

  Fly   462 QRPGSAQTTPVGYTYDTTHSPYSAGGPSPLAKIPKSGTSP------------------TPVAPNS 508
               ||.|..|:     .|..|.|:.|     .|..:|.||                  |.::.:|
  Fly   462 ---GSCQINPL-----KTSRPASSYG-----NISSTGISPKAKRKCYFYNNRGNDSDSTSMSTDS 513

  Fly   509 WAALRP--------------------------------QQQQQQQQPVTEGYQYQQT-------- 533
            ..:.:.                                |||||.|....:..|:||.
  Fly   514 VTSRQSMMTHVSSQSQRQRSHHREHHRENHHNQSHHHMQQQQQHQNQQQQHQQHQQLQQQLQHTV 578

  Fly   534 -SPARSPSGP-TYTQLSAGNGNRQQAQPGAYQAGPPPPPNAPGMWDWQQAGGHPHPPHPTAHPHH 596
             :|...|..| ..||:.|||. .|..|| ||....|... ||...:        .|.:.||.|..
  Fly   579 GTPKMVPLLPIASTQIMAGNA-CQFPQP-AYPLASPQLV-APTFLE--------PPQYLTAIPMQ 632

  Fly   597 PHAHPGGPAGAGQP---QGQEFSDML-QMLDHTPT 627
            |...|...|....|   |.|  :||| ..:..|||
  Fly   633 PVIAPFPVAPVLSPLPVQSQ--TDMLPDTVVMTPT 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tgo	NP_731308.1	bHLH-PAS_ARNT	9..74	CDD:381517	18/65 (28%)
		PAS	90..154	CDD:214512	21/63 (33%)
		PAS_11	282..384	CDD:464214	35/122 (29%)
Clk	NP_001014576.1	bHLH-PAS_dCLOCK	11..86	CDD:381578	21/81 (26%)
		PAS	93..153	CDD:214512	21/65 (32%)
		PAS_11	265..368	CDD:464214	35/103 (34%)