Protein Alignment tgo and bmal1b

DIOPT Version :10

• Sequence 1: NP_731308.1
• Gene: tgo / 41084
• FlyBaseID: FBgn0264075
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_005166673.1
• Gene: bmal1b / 352935
• ZFINID: ZDB-GENE-030408-1
• Length: 676
• Species: Danio rerio
• Alignment Length: 547
• Identity: 205/547 - (37%)
• Similarity: 307/547 - (56%)
• Gaps: 68/547 - (12%)

  Fly     8 DKERFASRENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVAHMKALRGTGNT 72
            |::...:||.|.:||:|||:||.::|.||:.:||||:|::||.||||:|||||.|||.|||..|.
Zfish   123 DQQMKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGAANP 187

  Fly    73 SSDGTYKPSFLTDQELKHLILEAADGFLFVVSCDSGRVIYVSDSVTPVLNYTQSDWYGTSLYEHI 137
            .::..|||:||:|.|||||||:|||||||||.||.|::::||:||..:|||:|:|..|.||::::
Zfish   188 YTEANYKPAFLSDDELKHLILKAADGFLFVVGCDRGKILFVSESVYKILNYSQNDLIGQSLFDYL 252

  Fly   138 HPDDREKIREQLSTQESQNAGRILDLKSG-TVKKEGHQSSMRLSMGARRGFICRMRVGNVNPESM 201
            ||.|..|::||||:.::....|::|.|:| .|:.:...|..||..||||.|.|||:..    .||
Zfish   253 HPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVRTDIAPSPSRLCSGARRSFFCRMKCN----RSM 313

  Fly   202 VSGHLNRLKQRNSLGPS------RDGTNYAVVHCTGYIKNWPPTDMFPNMHMERDVDDMSSHC-- 258
            |       |..:...||      .|..::..:|.|||:|:||||    .|.::.|.:..:..|
Zfish   314 V-------KMEDKDFPSTCSKKKADRKSFCTIHSTGYLKSWPPT----KMGLDEDNEPDNEGCNL 367

  Fly   259 -CLVAIGRLQ---VTSTAANDMSGSNNQSEFITRHAMDGKFTFVDQRVLNILGYTPTELLGKICY 319
             ||||||||.   |......|:  ....:|:::|||:||||.|||||...||.|.|.||||...|
Zfish   368 SCLVAIGRLHPHIVPQPVNGDI--RVKPTEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSFY 430

  Fly   320 DFFHPEDQSHMKESFDQVLKQKGQMFSLLYRARAKNSEYVWLRTQAYAFLNPYTDEVEYIVCTNS 384
            ::||.:|..|:.|...|||:.:.::.:..|:.:.|:..::.||::.::|:||:|.||||||.||:
Zfish   431 EYFHQDDIGHLAECHRQVLQMREKINTHCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNT 495

  Fly   385 SGKTMHGAPLDAAAAHTPEQVQQQQQQEQHVYVQA------APGVDYARRE-LTPVGSATNDGMY 442
               .:.|:.:|.|....| |:....|....|...|      .||:....|. ...:|....:.:.
Zfish   496 ---VVSGSSVDGAEPGFP-QLSASPQSMDSVLTAADGSGKTVPGLPGGTRAGAGKIGRMIAEEVM 556

  Fly   443 QTHMLAMQAPTPQQQQQQQQRPGSAQTTPVGYTYDTTHSPYSAGGPSPLAKIPKSGTSPTPVAPN 507
            :.|.:            :...|.|..::|:..: ::|..|.::   ||.|:  |.....||..|:
Zfish   557 EIHRI------------RGSSPSSCGSSPLNIS-NSTPPPDTS---SPAAR--KMSNGGTPDIPS 603

  Fly   508 SWAALRPQQQQQQQQPVTEGYQYQQTS 534
              |.|...|.       :.||.|..:|
Zfish   604 --AGLGSGQD-------SIGYPYSNSS 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tgo	NP_731308.1	bHLH-PAS_ARNT	9..74	CDD:381517	36/64 (56%)
		PAS	90..154	CDD:214512	36/63 (57%)
		PAS_11	282..384	CDD:464214	45/101 (45%)
bmal1b	XP_005166673.1	bHLH-PAS_ARNTL_PASD3	123..186	CDD:381444	36/62 (58%)
		PAS	205..264	CDD:214512	33/58 (57%)
		PAS_11	395..498	CDD:464214	46/105 (44%)