Protein Alignment tgo and Npas2

DIOPT Version :9

• Sequence 1: NP_001262397.1
• Gene: tgo / 41084
• FlyBaseID: FBgn0264075
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_038939510.1
• Gene: Npas2 / 316351
• RGDID: 1309681
• Length: 855
• Species: Rattus norvegicus
• Alignment Length: 612
• Identity: 157/612 - (25%)
• Similarity: 246/612 - (40%)
• Gaps: 135/612 - (22%)

  Fly     1 MDEANIQDKERFASRENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVA---- 61
            |||   .:|:| |.|.:..:.|::||::....|.|||.|:|   ...||.||.|:|...:.
  Rat     1 MDE---DEKDR-AKRASRNKSEKKRRDQFNVLIKELSSMLP---GNTRKLDKTTVLEKVIGFLQK 58

  Fly    62 HMKALRGTGNTSSDGTYKPSFLTDQELKHLILEAADGFLFVVSCDSGRVIYVSDSVTPVLNYTQS 126
            |.:....|........:|||||:::|...|:|||.|||:.||:.| |.:||||||:||:|.:..
  Rat    59 HNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFVIVVTTD-GSIIYVSDSITPLLGHLP- 121

  Fly   127 DWYGTS----------------LYEHIHPDDR---------------EKIREQLSTQESQNAGRI 160
               ||.                |...:||.:|               :.:...|..||.....:|
  Rat   122 ---GTEEESMKGLHRSRTLRLCLRSEVHPVERASFSLYFLLQSDVMDQNLLNFLPEQEHSEVYKI 183

  Fly   161 LD---LKSGTVKKEGHQSSMRLSMGARRGFICRMRVGNVNPESMVSGHLNRLKQRNSLGPSRDGT 222
            |.   |.:.:...|..:|...|.      |.|.:..|::||:...:....:.     :|..|...
  Rat   184 LSSHMLVTDSPSPEFLKSDNDLE------FYCHLLRGSLNPKEFPTYEYIKF-----VGNFRSYN 237

  Fly   223 NYAVVHCTGYIKNWPPTDMFPNMHMERDVDDMSSHCCLVAIGRLQVTSTAANDMSGSNNQSEFIT 287
            |.....|.|:..........|          :....|.:|..||.................||.:
  Rat   238 NVPSPSCNGFDNTLSRPCRVP----------LGKEVCFIATVRLATPQFLKEMCVADEPLEEFTS 292

  Fly   288 RHAMDGKFTFVDQRVLNILGYTPTELLGKICYDFFHPEDQSHMKESFDQVLKQKGQMFSLLYRAR 352
            ||:::.||.|:|.|...|:||.|.|:||...||::|.:|...:... .|.|.|.|:..|..||..
  Rat   293 RHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHIDDLELLARC-HQHLMQFGKGKSCCYRFL 356

  Fly   353 AKNSEYVWLRTQAYAFLNPYTDEVEYIVCTNSSGKTMHGAPLDAAAAHTPEQVQQQQQ------- 410
            .|..:::||:|..|...:.:..:.|:||||:|            ..::...:|:::|:
  Rat   357 TKGQQWIWLQTHYYITYHQWNSKPEFIVCTHS------------VVSYADVRVERRQELALEDPP 409

  Fly   411 ---------QEQHVYVQAAP---GVDYARRELT--PVGSATNDGMYQTHMLAMQAPTPQQQQQQQ 461
                     :|:...::..|   .:|.....||  |..||::...:::...||..||
  Rat   410 TEAMHPSALKEKDSSLEPQPHFNALDMGASGLTSSPSPSASSRSSHKSSHTAMSEPT-------- 466

  Fly   462 QRPGSAQTTPVGYTYD--TTHSPYSAGGPS--PLAKIPKSGTSPTPVAPNSWAALRPQQQQQQQQ 522
                   :||.....:  ||..|.||..|.  |:..:.::.|.|.|:..:|...| .:|...|..
  Rat   467 -------STPTKLMAENSTTALPRSATLPQELPVQGLSQAATMPAPLLSSSSCDL-AKQLLPQSL 523

  Fly   523 PVTEGYQYQQTSPARSPSGPTYTQLSA 549
            |.|         ..:||..|. ||.||
  Rat   524 PQT---------VLQSPPAPV-TQFSA 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tgo	NP_001262397.1	HLH	15..67	CDD:278439	17/55 (31%)
		PAS	87..192	CDD:279347	38/138 (28%)
		PAS	90..154	CDD:214512	28/94 (30%)
		PAS_11	283..384	CDD:291273	37/100 (37%)
		PAS	283..380	CDD:238075	33/96 (34%)
Npas2	XP_038939510.1	bHLH-PAS_NPAS2_PASD4	1..77	CDD:381580	24/82 (29%)
		PAS	84..234	CDD:395786	42/165 (25%)
		PAS_11	288..391	CDD:405306	38/115 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338218
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3561
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740