Protein Alignment tgo and clocka

DIOPT Version :9

• Sequence 1: NP_001262397.1
• Gene: tgo / 41084
• FlyBaseID: FBgn0264075
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_571032.2
• Gene: clocka / 30140
• ZFINID: ZDB-GENE-990630-14
• Length: 892
• Species: Danio rerio
• Alignment Length: 591
• Identity: 141/591 - (23%)
• Similarity: 237/591 - (40%)
• Gaps: 91/591 - (15%)

  Fly     2 DEANI------QDKERFASRENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAV 60
            |:::|      :|::..|.|.:....|::||::....|.||..|:|   ...||.||.|||:.::
Zfish     8 DDSSIFDGLMEEDEKDKAKRVSRNRSEKKRRDQFNVLIKELGTMLP---GNTRKMDKSTILQKSI 69

  Fly    61 ----AHMKALRGTGNTSSDGTYKPSFLTDQELKHLILEAADGFLFVVSCDSGRVIYVSDSVTPVL 121
                .|.:....:.::.....:||.||:::|...|:|||.|||...:..| |.:||||:|||.:|
Zfish    70 DFLRKHKEIAAQSESSEIRQDWKPPFLSNEEFTQLMLEALDGFFLAIMTD-GNIIYVSESVTSLL 133

  Fly   122 NYTQSDWYGTSLYEHIHPDDREKIREQLSTQESQNAGRILDLKSGTVKKEGHQSSMRLSMGARRG 186
            .:..||....:|...:...:..::.:.|||..         |:..|:..:..::..:|.
Zfish   134 EHLPSDLVDQNLLNFLPLGEHSEVYKALSTHM---------LEGETLTPDYLKTKNQLE------ 183

  Fly   187 FICRMRVGNVNPESMVSGHLNRLKQRNSLGPSRDGTNYAVVHCTGYIKNWPPTDMFPNMH----- 246
            |.|.|..|.::|:..                       .|.....:|.|:...:..||..
Zfish   184 FCCHMLRGTIDPKEP-----------------------PVYEYVKFIGNFKSLNTVPNSTRNGFE 225

  Fly   247 --MERDV-DDMSSHCCLVAIGRLQVTSTAANDMSGSNNQSEFITRHAMDGKFTFVDQRVLNILGY 308
              ::|.: .......|.:|..||..........:......||.:||:::.||.|:|.|...|:||
Zfish   226 GVIQRSLRHAFEDRVCFIATVRLAKPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGY 290

  Fly   309 TPTELLGKICYDFFHPEDQSHMKESFDQVLKQKGQMFSLLYRARAKNSEYVWLRTQAYAFLNPYT 373
            .|.|:||...||::|.:|...:.:..:. |.|.|:..|..||...|..:::||:|..|...:.:.
Zfish   291 LPFEVLGTSGYDYYHVDDLETLAKCHEH-LMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWN 354

  Fly   374 DEVEYIVCTN---SSGKTMHGAPLDAAAAHTPEQVQQQQQQEQHVYVQ--------AAPGVDYAR 427
            ...|:||||:   |..:.......:.....:|.::...:.|:.....|        |....|::|
Zfish   355 SRPEFIVCTHTVVSYAEVRAEQRRELGIEESPPEISADKSQDSGSESQLNTSSLKEALERFDHSR 419

  Fly   428 RELTPVGSATNDGMYQTHMLAMQAPTPQQQQQQQQR--PGSAQTTPVGYTYDTTHSPYSAGGPSP 490
               ||..|:.:.....:| .|:..||..|.:.|..|  |.....:.:..| ....|..|:...|.
Zfish   420 ---TPSASSRSSRKSSSH-TAVSDPTSTQTKLQTDRSTPPRQSVSAIEMT-SQRRSSISSQSMSS 479

  Fly   491 LAKIPKSGTSPTPVAPNSWAALRPQQQQQQQ---QPVTEGYQYQQTSPARSPSGPTYTQLSAGNG 552
            .......|||         ...:|||.|..|   |||.:..................|::...|.
Zfish   480 QTTGQTMGTS---------LVSQPQQPQTLQATVQPVLQFSTQMDAMQHLKEQLEQRTRMIEANI 535

  Fly   553 NRQQAQ 558
            .|||.:
Zfish   536 QRQQEE 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tgo	NP_001262397.1	HLH	15..67	CDD:278439	17/55 (31%)
		PAS	87..192	CDD:279347	29/104 (28%)
		PAS	90..154	CDD:214512	23/63 (37%)
		PAS_11	283..384	CDD:291273	36/103 (35%)
		PAS	283..380	CDD:238075	32/96 (33%)
clocka	NP_571032.2	HLH	23..77	CDD:238036	18/56 (32%)
		PAS	100..>169	CDD:279347	25/78 (32%)
		PAS	109..207	CDD:238075	28/136 (21%)
		PAS_11	265..368	CDD:291273	36/103 (35%)
		PAS	266..364	CDD:238075	35/98 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3561
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740