Protein Alignment CG11986 and HMCES

DIOPT Version :10

• Sequence 1: NP_649862.1
• Gene: CG11986 / 41083
• FlyBaseID: FBgn0037656
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: NP_064572.2
• Gene: HMCES / 56941
• HGNCID: 24446
• Length: 354
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 133/388 - (34%)
• Similarity: 197/388 - (50%)
• Gaps: 76/388 - (19%)

  Fly     1 MCGRTCLTLDPDQVICACKYPKKSTRKEPDFKEKDDMKDGEGSEMETPEWRAEYNLGRRYQASYN 65
            |||||...|..|.:..||.|                 :|..| :...||||..    .:|..|||
Human     1 MCGRTSCHLPRDVLTRACAY-----------------QDRRG-QQRLPEWRDP----DKYCPSYN 43

  Fly    66 IAPTDITPVIVSAAHF-SDAEDQECARVVTPMMWGMIPFWHK-GDYRRHGLTTNNCRLEHLMDSK 128
            .:|...:||::|..|| .||:..|  |::.||.||::|.|.| .|..:....|.|||.:.:|:.:
Human    44 KSPQSNSPVLLSRLHFEKDADSSE--RIIAPMRWGLVPSWFKESDPSKLQFNTTNCRSDTVMEKR 106

  Fly   129 LYRGPFKRGQRCVVICEGFYEWQTAGPAKKPSEREAYLVFVPQ----------AAD-----VKIY 178
            .::.|..:|:||||:.:||||||.   .:..::|:.|.::.||          |||     .|::
Human   107 SFKVPLGKGRRCVVLADGFYEWQR---CQGTNQRQPYFIYFPQIKTEKSGSIGAADSPENWEKVW 168

  Fly   179 DKNTWSPQDVKLLRMAGLFDVWE-DESGDKMYSYSIITFQSSKIMSWMHYRMPAILETEQQMNDW 242
            |  .|     :||.|||:||.|| .|.||.:|||:|||..|.|.:|.:|:||||||:.|:.::.|
Human   169 D--NW-----RLLTMAGIFDCWEPPEGGDVLYSYTIITVDSCKGLSDIHHRMPAILDGEEAVSKW 226

  Fly   243 LDFKRVSDKEALATLRPATELQWHRVTKLVNNSRNKSEECNKPIELAAKP--AKPPMNKTMMSWL 305
            |||..||.:|||..:.|...:.:|.|:.:||||||.:.||..|::|..|.  .....::.|:.||
Human   227 LDFGEVSTQEALKLIHPTENITFHAVSSVVNNSRNNTPECLAPVDLVVKKELRASGSSQRMLQWL 291

  Fly   306 NARKKREDQIKAKQSDDED---------QEKEATTMGGTSA----------DGSPVERPAKRP 349
            ..:..:::..|..|.::.|         |:....|..||:.          :..||   ||||
Human   292 ATKSPKKEDSKTPQKEESDVPQWSSQFLQKSPLPTKRGTAGLLEQWLKREKEEEPV---AKRP 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11986	NP_649862.1	SRAP	1..275	CDD:460605	108/291 (37%)
HMCES	NP_064572.2	SRAP	1..259	CDD:460605	108/291 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	292..354		13/63 (21%)
		PIP-box. /evidence=ECO:0000269|PubMed:30554877	332..338		0/5 (0%)