DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kcmf1 and Kcmf1

DIOPT Version :9

Sequence 1:	NP_001163560.1	Gene:	Kcmf1 / 41082	FlyBaseID:	FBgn0037655	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_001121664.1	Gene:	Kcmf1 / 684322	RGDID:	1591490	Length:	381	Species:	Rattus norvegicus

Alignment Length:	483	Identity:	212/483 - (43%)
Similarity:	259/483 - (53%)	Gaps:	147/483 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRHEGVSCDSCLKSNFNGRRYKCLICYDYDLCADCYEDGVTSTRHLVEHPMQCILTRSDIELYF 65
            ||||||||||:|||.||.||||||||||||||||.|||.|.|:|||..:|||||||||.|.:||:
  Rat     1 MSRHEGVSCDACLKGNFRGRRYKCLICYDYDLCASCYESGATTTRHTTDHPMQCILTRVDFDLYY 65

  Fly    66 GGEMLASDQPQSFTCPYCKKMGFSDATLLEHVSAEHTETSLEVVCPVCAGLPGGEPNLVTDDFAG 130
            |||..:.:||||||||||.|||:::.:|.|||::||.|||.||:||:||.||||:||.||||||.
  Rat    66 GGEAFSVEQPQSFTCPYCGKMGYTETSLQEHVTSEHAETSTEVICPICAALPGGDPNHVTDDFAA 130

  Fly   131 HLTLEHRQGPRELISFLDEPSAIRHGGGVRRI--PGRTLGGPRTRRSNMHFSSSS--GL----SA 187
            ||||||| .||:    |||.|.:||   |||:  |||.|||||.|||||||:|||  ||    |:
  Rat   131 HLTLEHR-APRD----LDESSGVRH---VRRMFHPGRGLGGPRARRSNMHFTSSSTGGLSSSQSS 187

  Fly   188 LSPSGRESVDPIAELLSQLSGVRR--------GGPPTSQLQQLQMQMQLDRQQVTASRQIDRLPR 244
            .|||.||::|||||||||||||||        .||..|||||||||:||:||...|:||.....|
  Rat   188 YSPSSREAMDPIAELLSQLSGVRRSAGGQLNSSGPSASQLQQLQMQLQLERQHAQAARQQLETAR 252

  Fly   245 RAHPIVSTSNSNAAMAEVISGGAGGSGGSGAVGSGSGGGSGATAPPNLRTTEWPVTASFSTSASN 309
            .|....:||:....:.:                        |||..|
  Rat   253 NASRRTNTSSVTTTITQ------------------------ATATAN------------------ 275

  Fly   310 HSQTQSSLAANSLNAREAIGTSSSAGSNVLGISVGVGGTANGNGGAGSSGVATGAGGAGQGGGQG 374
                    .||:.|:.:|:..|
  Rat   276 --------TANTENSPQALHNS------------------------------------------- 289

  Fly   375 GAAAGESFLLAQFMQPTFTEAEWAVVESMRADRSMFVQSLMLSML-------------------- 419
                  .|||.:...|..:|||...:||.|||||:|||.|:||.|
  Rat   290 ------QFLLTRLNDPKMSEAERQSMESERADRSLFVQELLLSTLVREESSSSDEDERGEMADFG 348

  Fly   420 ---CTEALDLNASDESLAKSDNVNKGQQ 444
               |.:.:.|:.:.|:|...:: |||.:
  Rat   349 AMGCVDIMPLDVALENLNLKES-NKGNE 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kcmf1	NP_001163560.1	ZZ_PCMF_like	7..55	CDD:239078	37/47 (79%)
Kcmf1	NP_001163560.1	zf-Di19	76..137	CDD:310299	43/60 (72%)
Kcmf1	NP_001121664.1	ZZ_PCMF_like	7..55	CDD:239078	37/47 (79%)
Kcmf1	NP_001121664.1	zf-Di19	76..137	CDD:398954	43/60 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	153	1.000	Domainoid score	I4204
eggNOG	1	0.900	-	-		E1_KOG1280
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004459
OrthoInspector	1	1.000	-	-		oto96298
orthoMCL	1	0.900	-	-		OOG6_107180
Panther	1	1.100	-	-	LDO	PTHR12268
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4843
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.770