Protein Alignment Kcmf1 and KCMF1

DIOPT Version :10

• Sequence 1: NP_649861.3
• Gene: Kcmf1 / 41082
• FlyBaseID: FBgn0037655
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: XP_006712115.1
• Gene: KCMF1 / 56888
• HGNCID: 20589
• Length: 389
• Species: Homo sapiens
• Alignment Length: 483
• Identity: 205/483 - (42%)
• Similarity: 254/483 - (52%)
• Gaps: 147/483 - (30%)

  Fly     1 MSRHEGVSCDSCLKSNFNGRRYKCLICYDYDLCADCYEDGVTSTRHLVEHPMQCILTRSDIELYF 65
            :...:|||||:|||.||.||||||||||||||||.|||.|.|:|||..:|||||||||.|.:||:
Human     9 LENDDGVSCDACLKGNFRGRRYKCLICYDYDLCASCYESGATTTRHTTDHPMQCILTRVDFDLYY 73

  Fly    66 GGEMLASDQPQSFTCPYCKKMGFSDATLLEHVSAEHTETSLEVVCPVCAGLPGGEPNLVTDDFAG 130
            |||..:.:||||||||||.|||:::.:|.|||::||.|||.||:||:||.||||:||.||||||.
Human    74 GGEAFSVEQPQSFTCPYCGKMGYTETSLQEHVTSEHAETSTEVICPICAALPGGDPNHVTDDFAA 138

  Fly   131 HLTLEHRQGPRELISFLDEPSAIRHGGGVRRI--PGRTLGGPRTRRSNMHFSSSS--GL----SA 187
            ||||||| .||:    |||.|.:||   |||:  |||.|||||.|||||||:|||  ||    |:
Human   139 HLTLEHR-APRD----LDESSGVRH---VRRMFHPGRGLGGPRARRSNMHFTSSSTGGLSSSQSS 195

  Fly   188 LSPSGRESVDPIAELLSQLSGVRR--------GGPPTSQLQQLQMQMQLDRQQVTASRQIDRLPR 244
            .|||.||::|||||||||||||||        .||..|||||||||:||:||...|:||.....|
Human   196 YSPSNREAMDPIAELLSQLSGVRRSAGGQLNSSGPSASQLQQLQMQLQLERQHAQAARQQLETAR 260

  Fly   245 RAHPIVSTSNSNAAMAEVISGGAGGSGGSGAVGSGSGGGSGATAPPNLRTTEWPVTASFSTSASN 309
            .|....:||:....:.:                        :||..|:..||           |:
Human   261 NATRRTNTSSVTTTITQ------------------------STATTNIANTE-----------SS 290

  Fly   310 HSQTQSSLAANSLNAREAIGTSSSAGSNVLGISVGVGGTANGNGGAGSSGVATGAGGAGQGGGQG 374
            ....|:|
Human   291 QQTLQNS---------------------------------------------------------- 297

  Fly   375 GAAAGESFLLAQFMQPTFTEAEWAVVESMRADRSMFVQSLMLSML-------------------- 419
                  .|||.:...|..:|.|...:||.|||||:|||.|:||.|
Human   298 ------QFLLTRLNDPKMSETERQSMESERADRSLFVQELLLSTLVREESSSSDEDDRGEMADFG 356

  Fly   420 ---CTEALDLNASDESLAKSDNVNKGQQ 444
               |.:.:.|:.:.|:|...:: |||.:
Human   357 AMGCVDIMPLDVALENLNLKES-NKGNE 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kcmf1	NP_649861.3	ZZ_PCMF_like	7..55	CDD:239078	37/47 (79%)
		zf-Di19	76..137	CDD:428539	43/60 (72%)
KCMF1	XP_006712115.1	ZZ_PCMF_like	15..63	CDD:239078	37/47 (79%)
		zf-Di19	84..145	CDD:428539	43/60 (72%)