DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kcmf1 and CG31642

DIOPT Version :9

Sequence 1:	NP_001163560.1	Gene:	Kcmf1 / 41082	FlyBaseID:	FBgn0037655	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_723159.1	Gene:	CG31642 / 326149	FlyBaseID:	FBgn0051642	Length:	557	Species:	Drosophila melanogaster

Alignment Length:	460	Identity:	111/460 - (24%)
Similarity:	169/460 - (36%)	Gaps:	96/460 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RHEGVSCDSCLKSNFNGRRYKCLICYDYDLCADCYEDG--VTSTRHLVEHPMQCILTRSDIELYF 65
            ||.|..|::|..|:|.||||.|..|.:|.||..|::..  ..|.:|...|||......::.:|||
  Fly    11 RHFGHRCENCKISDFQGRRYTCRFCAEYTLCGKCFDANHLPASPQHRYYHPMSVYYAYAEYQLYF 75

  Fly    66 GGEMLASDQ--PQSFTCPYCKKMGFSDATLLEHVSAEHTETSLEVVCPVCAGLPGGEPNLVTDDF 128
            |||....|.  .||:.|..|...|.|.|.|..|:..||.:..                     |.
  Fly    76 GGEPFCGDHKVAQSYKCALCDVRGLSTAHLFMHLLQEHRDHR---------------------DH 119

  Fly   129 AGHLTLEHR-----QGPRELISFLDEPSAIRHGGGVRRIPG-RTLGGPRTR---RSNMHFSSSSG 184
            ..:|:|.:.     .|..:.:. :.:||:.......|.:.. |.:.|..||   |:...|.|:..
  Fly   120 DAYLSLVNTLYIADNGMEQQVP-VPQPSSQTRSTRSRNLASVRPVAGGNTRSEQRTEQVFDSALS 183

  Fly   185 LSALSPSGRESVDPIA--------ELLSQLSGV----RRGGPPTSQLQQLQMQMQLDRQQVTASR 237
            | ||.....:::|..|        |:|.|...|    |....|  .::.::..:::...||..|
  Fly   184 L-ALMVVQLDNMDSTAADFPERCYEILQQTETVLMQHRSSRVP--DMEAIESFVRVIEDQVVTS- 244

  Fly   238 QIDRLPRRAHPIVSTSNSNAAMAEVISGGAGGSGGSGAVGSGSGGGSGATAPPNLRTTEWPVTAS 302
            ..||..|     :..|:|:......|...:.|:..:.|:|..:.               .||...
  Fly   245 MADRRQR-----LGASSSSLHRLTRIEAISPGTNTALAMGMRAA---------------MPVLVD 289

  Fly   303 FSTSASNHSQTQSSLAANSLNAREAIGTSSSAGSNVLGISVGVG-GTANGNGGAGSSGVATG--- 363
            ..|:.......:.:.....:..:.|:.:||.:|.  .|.|.||. ......|...:..|:|.
  Fly   290 QPTTMVRRQTARRTGEPIGIALQSAVASSSRSGK--AGSSSGVAKAQTKTQGDQPTKKVSTVITS 352

  Fly   364 --------AGGAGQGGGQGGAAAGESFLLAQFMQPTFTEAEWAVVESMRADRSMFVQSLMLSMLC 420
                    ......|.||    ..||.||    :.|||||.:.   ||.||..:|...:.|....
  Fly   353 PLKDKRFLCSKLVSGNGQ----KWESKLL----KATFTEAMFC---SMLADEELFQPPIGLPWTA 406

  Fly   421 TEALD 425
            ...||
  Fly   407 NFMLD 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kcmf1	NP_001163560.1	ZZ_PCMF_like	7..55	CDD:239078	19/49 (39%)
Kcmf1	NP_001163560.1	zf-Di19	76..137	CDD:310299	14/60 (23%)
CG31642	NP_723159.1	ZZ_PCMF_like	15..65	CDD:239078	19/49 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471872
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1280
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6024
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004459
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12268
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.790