DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Iru and YBR062C

DIOPT Version :9

Sequence 1:	NP_649859.1	Gene:	Iru / 41080	FlyBaseID:	FBgn0037653	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_009618.2	Gene:	YBR062C / 852354	SGDID:	S000000266	Length:	180	Species:	Saccharomyces cerevisiae

Alignment Length:	131	Identity:	34/131 - (25%)
Similarity:	60/131 - (45%)	Gaps:	35/131 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 GGVGGGGNSHMFFMGNPGDYAWGREGLDTIVTQMLNQMETSGPPPLSAQRINEI--------PNV 240
            |...|.|::|       .|        .|::.::|:||.   |..|..:.:.|:        |:.
Yeast    44 GNTSGEGDAH-------SD--------STLLLRLLSQML---PESLQEEWLQEMDKGKSAGCPDT 90

  Fly   241 ------QINAEEVNRKIQCSICWDDFKIDE--TVRKLP-CSHLYHENCIVPWLNLHSTCPICRKS 296
                  :||.:::.....||||:.::..||  .|.:|| |.|.:...|:..||:..:|||:||.:
Yeast    91 FAASLPRINKKKLKATDNCSICYTNYLEDEYPLVVELPHCHHKFDLECLSVWLSRSTTCPLCRDN 155

  Fly   297 L 297
            :
Yeast   156 V 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Iru	NP_649859.1	zinc_ribbon_9	16..46	CDD:373030
		RING-H2_RNF126_like	252..294	CDD:319581	17/44 (39%)
		HRD1	<253..372	CDD:227568	19/48 (40%)
		RING-H2 finger (C3H2C3-type)	253..293	CDD:319581	17/42 (40%)
YBR062C	NP_009618.2	RING_Ubox	109..153	CDD:418438	17/43 (40%)
YBR062C	NP_009618.2	RING-H2 finger (C3H2C3-type)	109..152	CDD:319361	17/42 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910