Protein Alignment Iru and ATL15

DIOPT Version :10

• Sequence 1: NP_649859.1
• Gene: Iru / 41080
• FlyBaseID: FBgn0037653
• Length: 380
• Species: Drosophila melanogaster
• Sequence 2: NP_173666.1
• Gene: ATL15 / 838856
• AraportID: AT1G22500
• Length: 381
• Species: Arabidopsis thaliana
• Alignment Length: 933
• Identity: 167/933 - (17%)
• Similarity: 287/933 - (30%)
• Gaps: 334/933 - (35%)

  Fly    32 DGDKYRELYCPSKNIPKWLDGYFLCQLSASYGN------------------SSAPEGEKLN---- 74
            :.|:..:|..|.:.        |.|..|...|:                  ||:|.|:.|.
plant   877 EADECHDLESPIQE--------FFCSSSPMGGSMRQNKRRRILEKPTRRELSSSPGGDILESDYV 933

  Fly    75 ------------HMID--------AIGAVGSFH--VSNGQVVFSAQYYPARPYKIWEFYDRNMSK 117
                        |.:|        .||:..|.|  |...:::.||.....|      |.:.::.:
plant   934 REAVHHREEAACHNVDNYDVELQKLIGSASSHHYSVELQKMIGSASSAELR------FEEGDILE 992

  Fly   118 ASVPWAGWSDYNLTAMSRWEQVPA-NPD------------SARFHPNLDFWK-VGNRI------- 161
                    |||...|:...|:... |.|            ::..|.:::..| :|:..
plant   993 --------SDYVREAVHHREEAACHNVDNYDVELQKLIGSASSHHYSVELQKMIGSASSAELRFE 1049

  Fly   162 ------VAGTEAPYWVGYEFDVRTLQKFKL-------------FPFKEE----------NDIFST 197
                  .||..:|..:.|..:..::|:.::             ||:..|          .|..|:
plant  1050 ESYLLKEAGLMSPASLSYRTEQLSVQRSQIAPDHRVGSENINFFPYAGETSHGLASCIVRDSDSS 1114

  Fly   198 PRHTMIPISMAIHERNDADGTIWGSFSAMNFEEQRFFQGIFTVDTNGVRRVVGLYDYGVWDTNAC 262
            |  .:.|:.:.    :..||:            ....:| |.:.|:              |.|..
plant  1115 P--CLTPLGLI----SSDDGS------------PPVLEG-FIIQTD--------------DENQS 1146

  Fly   263 GSNDEYIGDKTLLPGYIHSITSTENFIILPITSLLINPCK---FKEPPLNNVRSAIQKGGLWGMD 324
            ||.::...|...||.     |:.|:      .:::...||   ...|.|:..::
plant  1147 GSKNQLNHDSFQLPR-----TTAES------AAMIEQICKSACMNTPSLHLAKT----------- 1189

  Fly   325 FYDMVPMRFLIFNKKTLEFTTSKPLEVFPSMFVTHQLNAFEADDGNFVADMVVYDSHDPYVKYFY 389
                     ..|::| |:...|...|:|..||.:..|      :|:.|.|.:.. :|| |....|
plant  1190 ---------FKFDEK-LDLDQSVSTELFDGMFFSQNL------EGSSVFDNLGI-NHD-YTGRSY 1236

  Fly   390 TDFLTKQLYPST--ARVLRFTLDSKKQRVMYNYL------VPQETIAADFP---QFNHNYEQKPY 443
            ||.|     |.|  :...|....|..:::.|..|      ..:.|...|.|   :.|.|.|::..
plant  1237 TDSL-----PGTGSSAEARNPCMSPTEKLWYRSLQKSSSSEKRSTQTPDLPCISEENENIEEEAE 1296

  Fly   444 QWGYLVQHPFAS---GNSIIKI--------NVDEPAGNRNLEFRAEPTLVLHEPWFVQKPDSKKE 497
            ...........|   |:||.::        |:||.:...|....:|...|..|    :||.....
plant  1297 NLCTNTPKSMRSEKRGSSIPELPCIAEENENIDEISDAVNEASGSERENVSAE----RKPLGDVN 1357

  Fly   498 DEGVLIVRGLDTAENKGVLIVIDAEKMVELGRAYVPISIPFGFHNRFFSKKDLGLPEGFQVGQSQ 562
            ::.:.::..:..|:       |.|::     ::...:|..|.|..:..|.|.       :||:..
plant  1358 EDPMKLLPSVSEAK-------IPADR-----QSLDSVSTAFSFSAKCNSVKS-------KVGKLS 1403

  Fly   563 YRPI----EKKQGFATLPLRKVSTVPPTTSTSSTTTQKPSTTTTVPSTTPTSTTTTTTTTPKPTT 623
            .|..    ::.||.|.   .|.:..||::..|.......|:.|||.......       .|:...
plant  1404 NRRFTGKGKENQGGAG---AKRNVKPPSSRFSKPKLSCNSSLTTVGPRLQEK-------EPRHNN 1458

  Fly   624 STSTSTSTTTTTTTSTTATTTPQPTTTTTSEKPVTLTTQTWTAPPTTTVKRTTPQTVPTTTPKIP 688
            ..|..||.                         |.|..|...||...|.||..         |:.
plant  1459 IVSNITSF-------------------------VPLVQQQKPAPALITGKRDV---------KVK 1489

  Fly   689 RWWPLAGSGSTEQPWWQKVQTGQNTLPPLFPVSKRVEE----KVEKVSAKPNESDNKIPEQKPVT 749
               .|..:.::::...|| :..:........:.:..:|    |.:::..|..|.|.|..|.
plant  1490 ---ALEAAEASKRIAEQK-ENDRKLKKEAMKLERAKQEQENLKKQEIEKKKKEEDRKKKEA---- 1546

  Fly   750 ATGSMDEIYEQTLGALCSWLPKVFTSISNELCWKQGKTAAKWMAPLAQTYAERFRMGRANRKVSP 814
                                         |:.|||.....|   ...:...:.|.|....|:...
plant  1547 -----------------------------EMAWKQEMEKKK---KEEERKRKEFEMADRKRQREE 1579

  Fly   815 NDTPNLQPSLKQMAFDEQQQQAE 837
            .|....:...:|...|.|:||.|
plant  1580 EDKRLKEAKKRQRIADFQRQQRE 1602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Iru	NP_649859.1	zinc_ribbon_9	16..46	CDD:433910	3/13 (23%)
		RING-H2_RNF126-like	252..294	CDD:438329	9/41 (22%)
		HRD1	<253..372	CDD:227568	23/121 (19%)
ATL15	NP_173666.1	RAD18	116..>217	CDD:227719
		RING-H2_EL5-like	117..160	CDD:438124