DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Iru and RHC1A

DIOPT Version :9

Sequence 1:	NP_649859.1	Gene:	Iru / 41080	FlyBaseID:	FBgn0037653	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_001324188.1	Gene:	RHC1A / 818680	AraportID:	AT2G40830	Length:	328	Species:	Arabidopsis thaliana

Alignment Length:	367	Identity:	86/367 - (23%)
Similarity:	137/367 - (37%)	Gaps:	96/367 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FCHMCNVEINIPNSDFTCPLCANGFVEELPANAPEMDSSTAGASGSARSGSSGSGSSGSHDTLSR 82
            :||.|...:.:...:..|..|..||||||       |.:.|......||.........:.|.:..
plant     9 WCHRCQRAVRLHGQEPVCFYCGGGFVEEL-------DMAQASPFDMFRSHRGVVERDQTFDLMDA 66

  Fly    83 GSSSSGSQVNVESLRNDIVSLLNMRNVPNLEITIEPNRRHSNVLHLGGFGGPSGSDSARGLTA-- 145
            .|         ..:||.:....:.|.:....|:                   ||.::..||..
plant    67 FS---------VFMRNRLAERSHDREIRGRTIS-------------------SGPENFPGLAPLL 103

  Fly   146 --GGRVRPANLDRLDNVLFDFLQSLPLAGATAEIVTGPGGGGVGGGGNSHMFFMGNPGDYAWGRE 208
              ||:| |..|.. ||.:              |.:...|..|:|       ...||.|||.:| .
plant   104 IFGGQV-PYRLTG-DNAV--------------EALFNGGSPGIG-------ITRGNTGDYFFG-P 144

  Fly   209 GLDTIVTQMLNQMETSGPPPLSAQRINEIPNVQINAEEV-NRKIQCSICWDDFKIDETVRKLPCS 272
            ||:.:..|:.......||||.....|:.:|.::|....: :....|.:|.|:|::....:::||:
plant   145 GLEELFEQLSAGTTRRGPPPAPRSAIDALPTIKIAQRHLRSSDSNCPVCKDEFELGSEAKQMPCN 209

  Fly   273 HLYHENCIVPWLNLHSTCPICRKSLADDGNDADDEFVMLDAFGPEMAADGSNSERR-----SAST 332
            |:||.:||||||..|::||:||:.|.             .|.||..:.:.:...|.     |:|:
plant   210 HIYHSDCIVPWLVQHNSCPVCRQELP-------------SASGPSSSQNRTTPTRNYRSSSSSSS 261

  Fly   333 ATGTDNPSPANNP--------------SQAAAEGGRTRPDAN 360
            :...:|.:...||              |.....||....|.:
plant   262 SNSRENGNERRNPFSSFWPFRSSGSSSSSTQNRGGTRNSDTS 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Iru	NP_649859.1	zinc_ribbon_9	16..46	CDD:373030	9/27 (33%)
		RING-H2_RNF126_like	252..294	CDD:319581	18/41 (44%)
		HRD1	<253..372	CDD:227568	34/127 (27%)
		RING-H2 finger (C3H2C3-type)	253..293	CDD:319581	18/39 (46%)
RHC1A	NP_001324188.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	72	1.000	Domainoid score	I3298
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1871
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1249953at2759
OrthoFinder	1	1.000	-	-		FOG0000184
OrthoInspector	1	1.000	-	-		otm2990
orthoMCL	1	0.900	-	-		OOG6_102823
Panther	1	1.100	-	-	O	PTHR15710
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X390
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.930