DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Iru and rnf38

DIOPT Version :9

Sequence 1:	NP_649859.1	Gene:	Iru / 41080	FlyBaseID:	FBgn0037653	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	XP_021331935.1	Gene:	rnf38 / 566820	ZFINID:	ZDB-GENE-030131-8693	Length:	676	Species:	Danio rerio

Alignment Length:	93	Identity:	29/93 - (31%)
Similarity:	50/93 - (53%)	Gaps:	4/93 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 MLNQMETSG---PPPLSAQRINEIPNVQIN-AEEVNRKIQCSICWDDFKIDETVRKLPCSHLYHE 277
            :||..|..|   |..|:...|.::|:.:.| :...:.:..|.:|..||:..:.:|.|||:|.:|.
Zfish   584 LLNLAERLGEAKPRGLTKADIEQLPSYRFNPSNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHA 648

  Fly   278 NCIVPWLNLHSTCPICRKSLADDGNDAD 305
            .|:..||..:.||||||...::...|::
Zfish   649 KCVDKWLKANRTCPICRADASEVQRDSE 676

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Iru	NP_649859.1	zinc_ribbon_9	16..46	CDD:373030
		RING-H2_RNF126_like	252..294	CDD:319581	17/41 (41%)
		HRD1	<253..372	CDD:227568	20/53 (38%)
		RING-H2 finger (C3H2C3-type)	253..293	CDD:319581	16/39 (41%)
rnf38	XP_021331935.1	RING-H2_RNF38_like	621..665	CDD:319386	17/43 (40%)
rnf38	XP_021331935.1	RING-H2 finger (C3H2C3-type)	624..664	CDD:319386	16/39 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910