Protein Alignment Iru and rlim

DIOPT Version :10

• Sequence 1: NP_649859.1
• Gene: Iru / 41080
• FlyBaseID: FBgn0037653
• Length: 380
• Species: Drosophila melanogaster
• Sequence 2: XP_686027.4
• Gene: rlim / 562487
• ZFINID: ZDB-GENE-120809-2
• Length: 638
• Species: Danio rerio
• Alignment Length: 323
• Identity: 84/323 - (26%)
• Similarity: 121/323 - (37%)
• Gaps: 82/323 - (25%)

  Fly    41 GFVEELPANAPEMDSST--AGASG-------------SARSGSSGSGSSGSHDTLSRGSSSSGSQ 90
            |...::|....|.:::|  |||||             ..|.|......|.::.|.|| |.:|.:.
Zfish   322 GSATDVPEAPQEREATTGEAGASGRRPPTIMLDLQVRRVRPGEYRQRDSIANRTRSR-SQTSNNT 385

  Fly    91 VNVESLRNDI---VSLLNMRNVPNLEITIE-PNRRHSNVLHLGGFGGPSGSDSARGLTAGGRVRP 151
            :..|:.|...   .|......|.....||. |.||.|:          :|...|..|.....:|.
Zfish   386 LLYETERGGFRRTFSRSERAGVRTYVSTIRIPIRRISD----------AGLGEATSLALQSMIRQ 440

  Fly   152 ----------------ANLDRLDNVLFDFLQSLPLAGATAEIVTG--------PGGGGVGGGG-- 190
                            .:.:|.||...|.  |..|....|...||        ||.||:..||
Zfish   441 IMTGFGELSYFMEAEVPDSNREDNPPADL--SDALGNPDASTGTGASEADPYLPGHGGLNQGGLE 503

  Fly   191 ---NSHMFFMGNPGDYAWGRE---------GLDTIVTQ---------MLNQMETSGPPPLSAQRI 234
               .......|.|| .|..||         .||...:.         :||:.:...|..|:.::|
Zfish   504 ARTEEREVEGGLPG-AAGPRENRGRQRAPINLDETGSLPFLRLAHFFLLNEEDDDQPRGLTKEQI 567

  Fly   235 NEIPNVQINAEEVNRKIQCSICWDDFKIDETVRKLPCSHLYHENCIVPWLNLHSTCPICRKSL 297
            :.:.  ..|..|.:....||:|..::.....:|||||||.||.:||..||:.:|||||||:::
Zfish   568 DNLS--MRNFGESDAFKTCSVCITEYAEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAV 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Iru	NP_649859.1	zinc_ribbon_9	16..46	CDD:433910	1/4 (25%)
		RING-H2_RNF126-like	252..294	CDD:438329	21/41 (51%)
		HRD1	<253..372	CDD:227568	23/45 (51%)
rlim	XP_686027.4	RING-H2_RNF12	582..631	CDD:438336	23/47 (49%)