Protein Alignment Iru and rnf126

DIOPT Version :9

• Sequence 1: NP_649859.1
• Gene: Iru / 41080
• FlyBaseID: FBgn0037653
• Length: 380
• Species: Drosophila melanogaster
• Sequence 2: XP_031753815.1
• Gene: rnf126 / 448402
• XenbaseID: XB-GENE-5960892
• Length: 337
• Species: Xenopus tropicalis
• Alignment Length: 363
• Identity: 117/363 - (32%)
• Similarity: 170/363 - (46%)
• Gaps: 72/363 - (19%)

  Fly     1 MAEAMVVEDRPAEAKRFFCHMCNVEINIPN-SDFTCPLCANGFVEELPANAPEMDSSTAGASGSA 64
            ||||:      .||.|:|||.|..|| ||. .::|||.|.:||:|||| .....:::::..||:.
 Frog    27 MAEAL------PEAGRYFCHSCTAEI-IPRLPEYTCPRCDSGFIEELP-ETRNSENNSSNNSGTD 83

  Fly    65 RSGSSGSGSSGSHDTLSRGSSS--------------SGSQVNVESLRNDIVSLLNMRNVPNLEIT 115
            ::..|......:..||..|...              .|:...||..|:.
 Frog    84 QNRPSFENLESAQFTLPSGYGQVTFGIFNEGLDFPIFGTSGPVEEPRDG---------------- 132

  Fly   116 IEPNRRHSNVLHLGGFGGPSGSDSARGLTAGGRVRPANLDRLDNVLFDFLQSLPLAGATAEIVTG 180
             |..|.|.:....|     :....||..|.....|...:..|:.::...:..:....|.:.:
 Frog   133 -ESRREHQSRQRYG-----ARQPRARLSTRRAAGRNEGVPTLEGIIQQLVNGIIAPTAMSNL--- 188

  Fly   181 PGGGGVGGGGNSHMFFMGNPGDYAWGREGLDTIVTQMLNQMETSGPPPLSAQRINEIPNVQINAE 245
                |||..|..|    .||.|||||..|||||:||:|||.|.:||||...::|..:|.:||..|
 Frog   189 ----GVGPWGVLH----SNPMDYAWGANGLDTIITQLLNQFENTGPPPADTEKIQALPTIQITEE 245

  Fly   246 EVNRKIQCSICWDDFKIDETVRKLPCSHLYHENCIVPWLNLHSTCPICRKSLADDGNDADDEFVM 310
            .|...::|.:|.:|:.:.|:||:|||:||:|.:||:|||..|.|||:|||||:....
 Frog   246 HVGSGLECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSLSGQNT-------- 302

  Fly   311 LDAFGP----EMAADGSNSERRSASTATGTDNPSPANN 344
              |..|    ||..  |:|...|:|:.:.||..:.|||
 Frog   303 --ATNPPGLTEMTF--SSSSTSSSSSTSPTDENNAANN 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Iru	NP_649859.1	zinc_ribbon_9	16..46	CDD:373030	16/30 (53%)
		RING-H2_RNF126_like	252..294	CDD:319581	21/41 (51%)
		HRD1	<253..372	CDD:227568	39/96 (41%)
		RING-H2 finger (C3H2C3-type)	253..293	CDD:319581	21/39 (54%)
rnf126	XP_031753815.1	zinc_ribbon_9	36..66	CDD:405118	16/30 (53%)
		RING-H2_RNF126	252..295	CDD:319715	22/42 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	73	1.000	Domainoid score	I9056
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H27024
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3860
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1249953at2759
OrthoFinder	1	1.000	-	-		FOG0000184
OrthoInspector	1	1.000	-	-		otm48528
Panther	1	1.100	-	-	O	PTHR15710
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1936
SonicParanoid	1	1.000	-	-		X390
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.100