DRSC/TRiP Functional Genomics Resources

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Protein Alignment Iru and Rnf115

DIOPT Version :9

Sequence 1:NP_649859.1 Gene:Iru / 41080 FlyBaseID:FBgn0037653 Length:380 Species:Drosophila melanogaster
Sequence 2:XP_006233037.2 Gene:Rnf115 / 362002 RGDID:1305315 Length:423 Species:Rattus norvegicus


Alignment Length:363 Identity:115/363 - (31%)
Similarity:160/363 - (44%) Gaps:81/363 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MAEAMVV---EDRPAEAKRFFCHMCNVEINIPNSDFTCPLCANGFVEELPANAPEMDSSTAGASG 62
            ||||...   ......|.|||||.|..|:|....::.||.|.:||:||:..     |||..|..|
  Rat   119 MAEASAAGADAGSAVAAHRFFCHFCKGEVNPKLPEYICPRCESGFIEEVTD-----DSSFLGGGG 178

  Fly    63 SARSGSSGSGSSGSHDTLSRGSSSSGSQVNVESLRNDIVS-LLNMRNVPNLEITIEPNRRHSNVL 126
            |....|:.:..:...|.|..       .:.::..|..:.| .|:..|..|       .|.|....
  Rat   179 SRTDNSTATHFAELWDHLDH-------TMFLQDFRPFLSSNPLDQDNRAN-------ERGHQTHT 229

  Fly   127 HLGGFGGPSGSDSARGLTAGGRVRPANLDRLDNVLFDFLQSLPLAGATAEIVTG-------PGGG 184
            ...|...|......|...:.|..||   ||          |..:.|...:|..|       |   
  Rat   230 DFWGPSRPPRLPMTRRYRSRGSTRP---DR----------SPAIEGIIQQIFAGFFANSAIP--- 278

  Fly   185 GVGGGGNSHMF-----FMGNPGDYAWGREGLDTIVTQMLNQMETSGPPPLSAQRINEIPNVQINA 244
                 |:.|.|     ...||||||||:.|||.||||:|.|:|.:||||...::|..:|.|.:..
  Rat   279 -----GSPHPFSWSGMLHSNPGDYAWGQTGLDAIVTQLLGQLENTGPPPADKEKITSLPTVTVTQ 338

  Fly   245 EEVNRKIQCSICWDDFKIDETVRKLPCSHLYHENCIVPWLNLHSTCPICRKSLADDGNDADDEFV 309
            |:||..::|.:|.:|:.::|.||:|||:|.:|.:||||||.||.|||:|||||            
  Rat   339 EQVNTGLECPVCKEDYTVEEKVRQLPCNHFFHSSCIVPWLELHDTCPVCRKSL------------ 391

  Fly   310 MLDAFGPEMAADGSNSERRSASTATGTDNPSPANNPSQ 347
                       :|.:|.|::.|:.....|  ..:|.||
  Rat   392 -----------NGEDSTRQTQSSEASASN--RFSNDSQ 416

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IruNP_649859.1 zinc_ribbon_9 16..46 CDD:373030 14/29 (48%)
RING-H2_RNF126_like 252..294 CDD:319581 22/41 (54%)
HRD1 <253..372 CDD:227568 35/95 (37%)
RING-H2 finger (C3H2C3-type) 253..293 CDD:319581 22/39 (56%)
Rnf115XP_006233037.2 zinc_ribbon_9 137..167 CDD:405118 14/29 (48%)
RING-H2_RNF115 345..391 CDD:319714 25/45 (56%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 73 1.000 Domainoid score I9029
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 171 1.000 Inparanoid score I4022
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1249953at2759
OrthoFinder 1 1.000 - - FOG0000184
OrthoInspector 1 1.000 - - otm45453
orthoMCL 1 0.900 - - OOG6_102823
Panther 1 1.100 - - LDO PTHR15710
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X390
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
1110.970

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