Protein Alignment Iru and rnf128a

DIOPT Version :10

• Sequence 1: NP_649859.1
• Gene: Iru / 41080
• FlyBaseID: FBgn0037653
• Length: 380
• Species: Drosophila melanogaster
• Sequence 2: NP_997780.1
• Gene: rnf128a / 322325
• ZFINID: ZDB-GENE-030131-1044
• Length: 389
• Species: Danio rerio
• Alignment Length: 300
• Identity: 58/300 - (19%)
• Similarity: 100/300 - (33%)
• Gaps: 118/300 - (39%)

  Fly   131 FGGPSGSDSARGLTAGGRVRPANLDRLDNVLFDFLQSLPLA---GATAEIVTGPGGGGVGGGGNS 192
            :|.|:||.....|...|..            ..|.:.:.:|   ||.|.|:..      ..|..:
Zfish    87 YGRPNGSKGWIALIQRGNG------------CTFTEKINIAAMNGAAAAIIFN------DFGSEN 133

  Fly   193 HMFFMGNPGDYAWGREGLDTIVTQMLN--------QMETSGPPP--------------------- 228
            .:..|.:||         .|||..|:.        |:...|.|.
Zfish   134 RVIQMSHPG---------TTIVAIMIGNYRGMELVQLLDQGVPVAIAIEVGKQHGPWMSHYSVFF 189

  Fly   229 ------------------LSAQRINEI-------PNVQINAEEVNRKIQ---------------- 252
                              .||:|:|.:       ..::..|::...::|
Zfish   190 VSISFFIVTAATVGYFIFYSARRLNSLRQQNRSQKKLKAEAKKAIGQLQVRTLRQGDQEIGPDAD 254

  Fly   253 -CSICWDDFKIDETVRKLPCSHLYHENCIVPWLNLHSTCPICRKSLADDGNDADDEFVMLDAFGP 316
             |::|.|.:|..:.:..|.|:|.:|::||.|||..|.|||:|:..:             |.|.|.
Zfish   255 ACAVCIDSYKAGDVLSILTCNHFFHKSCIEPWLLEHRTCPMCKCDI-------------LKALGV 306

  Fly   317 EMAADG----SNSERRSASTATGTDNPSPANNPSQAAAEG 352
            |:..:.    |..:.|..||:....:.:.::..|:.|:.|
Zfish   307 ELDVEEQPQISVPDFRPFSTSEDLHSETASHTHSETASSG 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Iru	NP_649859.1	zinc_ribbon_9	16..46	CDD:433910
		RING-H2_RNF126-like	252..294	CDD:438329	18/58 (31%)
		HRD1	<253..372	CDD:227568	28/103 (27%)
rnf128a	NP_997780.1	PA_GRAIL_like	38..172	CDD:239037	23/111 (21%)
		HRD1	<185..>297	CDD:227568	23/111 (21%)
		RING-H2_RNF128-like	254..302	CDD:438454	18/60 (30%)