DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta3 and PSMB7

DIOPT Version :9

Sequence 1:	NP_649858.1	Gene:	Prosbeta3 / 41079	FlyBaseID:	FBgn0026380	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_002790.1	Gene:	PSMB7 / 5695	HGNCID:	9544	Length:	277	Species:	Homo sapiens

Alignment Length:	201	Identity:	39/201 - (19%)
Similarity:	77/201 - (38%)	Gaps:	30/201 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GGCVVAMRGKDCVAIATDHRFGIQAQTISTDFKKVFHIGPRMFL--GLTGLQTDILTVRDRLMFR 70
            |..:..:..||.:.:..|.|..........:..|:..|.|.::.  ..|...||:.|    .:..
Human    43 GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTT----QLIS 103

  Fly    71 KNLYETRENREMCPKPFSA--MMSSFLYEHRFGPYFIEPVVAGLDPKTMEPFICNMDLIG----- 128
            .||.....:....|:..:|  |:...|:  |:..|....:|.|           .:|:.|
Human   104 SNLELHSLSTGRLPRVVTANRMLKQMLF--RYQGYIGAALVLG-----------GVDVTGPHLYS 155

  Fly   129 -CPNAPDD---FVVAGTCAEQLYGMCETLWKPDLEPDQLFEVIAQSIVNAFDRDAMSGWGATVYI 189
             .|:...|   :|..|:.:.....:.|..::||:|.::...:::::|......|..||....:.:
Human   156 IYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCV 220

  Fly   190 IEKDKI 195
            |.|:|:
Human   221 ISKNKL 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta3	NP_649858.1	proteasome_beta_type_3	6..201	CDD:239728	39/201 (19%)
PSMB7	NP_002790.1	proteasome_beta_type_7	44..232	CDD:239732	38/200 (19%)
PSMB7	NP_002790.1	Pr_beta_C	236..271	CDD:403609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810