DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta3 and PSMA4

DIOPT Version :9

Sequence 1:	NP_649858.1	Gene:	Prosbeta3 / 41079	FlyBaseID:	FBgn0026380	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_001096137.1	Gene:	PSMA4 / 5685	HGNCID:	9533	Length:	261	Species:	Homo sapiens

Alignment Length:	124	Identity:	27/124 - (21%)
Similarity:	54/124 - (43%)	Gaps:	19/124 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSILAYNGGCVVAMRGKDCVAIATDHRFGIQAQTISTDF-KKVFHIGPRMFLGLTGLQTD--ILT 62
            |..:.:.|.| :.:...|.|.:|.:.| .|........| :|::.:...|...:.|:.:|  :||
Human    25 MEAIGHAGTC-LGILANDGVLLAAERR-NIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLT 87

  Fly    63 VRDRLMFRKNLYETRENREMCPKPFSAMMSSF-----LYEHRFG---PYFIEPVVAGLD 113
            ...||:.::.|.:.:|     |.|...::::.     .|. :||   |:.:..:..|.|
Human    88 NELRLIAQRYLLQYQE-----PIPCEQLVTALCDIKQAYT-QFGGKRPFGVSLLYIGWD 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta3	NP_649858.1	proteasome_beta_type_3	6..201	CDD:239728	26/119 (22%)
PSMA4	NP_001096137.1	proteasome_alpha_type_4	3..216	CDD:239721	27/124 (22%)
PSMA4	NP_001096137.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	240..261
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900