DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta3 and pup3

DIOPT Version :9

Sequence 1:	NP_649858.1	Gene:	Prosbeta3 / 41079	FlyBaseID:	FBgn0026380	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_587985.1	Gene:	pup3 / 2539401	PomBaseID:	SPCC63.12c	Length:	204	Species:	Schizosaccharomyces pombe

Alignment Length:	205	Identity:	109/205 - (53%)
Similarity:	150/205 - (73%)	Gaps:	1/205 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSILAYNGGCVVAMRGKDCVAIATDHRFGIQAQTISTDFKKVFHIGPRMFLGLTGLQTDILTVRD 65
            |||:.||||..|||.||:|||||:|.|.|:|:.:::.:|.|||.:|.:.:||||||.||:.|:.:
pombe     1 MSIMEYNGGSCVAMAGKNCVAIASDLRLGVQSISLTNNFPKVFAMGDKTYLGLTGLATDVQTLYE 65

  Fly    66 RLMFRKNLYETRENREMCPKPFSAMMSSFLYEHRFGPYFIEPVVAGLDPKTMEPFICNMDLIGCP 130
            ...::.|||:.||.|::.||.|:.::||.|||.||||||..|||||:. ....||||..|.|||.
pombe    66 LFRYKVNLYKFREERQIQPKTFANLVSSTLYEKRFGPYFSFPVVAGVS-NDNTPFICGFDSIGCI 129

  Fly   131 NAPDDFVVAGTCAEQLYGMCETLWKPDLEPDQLFEVIAQSIVNAFDRDAMSGWGATVYIIEKDKI 195
            :..:||:|:||..||||||||::::|:||||.|||.|:|:::||.|||.:||||..||:|..||.
pombe   130 DFAEDFIVSGTATEQLYGMCESVYEPNLEPDDLFETISQALLNAQDRDCISGWGCVVYVITADKC 194

  Fly   196 TERTLKTRMD 205
            .:|.:|.|.|
pombe   195 IKRLVKGRQD 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta3	NP_649858.1	proteasome_beta_type_3	6..201	CDD:239728	103/194 (53%)
pup3	NP_587985.1	PRE1	3..200	CDD:223711	104/197 (53%)
pup3	NP_587985.1	proteasome_beta_type_3	6..200	CDD:239728	103/194 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	210	1.000	Domainoid score	I606
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2089
Inparanoid	1	1.050	228	1.000	Inparanoid score	I868
OMA	1	1.010	-	-		QHG53924
OrthoFinder	1	1.000	-	-		FOG0003566
OrthoInspector	1	1.000	-	-		oto100461
orthoMCL	1	0.900	-	-		OOG6_101970
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1011
SonicParanoid	1	1.000	-	-		X2440
TreeFam	1	0.960	-	-
	14	13.860