DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prosbeta3 and Psmb7

DIOPT Version :9

Sequence 1:	NP_649858.1	Gene:	Prosbeta3 / 41079	FlyBaseID:	FBgn0026380	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_035317.1	Gene:	Psmb7 / 19177	MGIID:	107637	Length:	277	Species:	Mus musculus

Alignment Length:	199	Identity:	37/199 - (18%)
Similarity:	74/199 - (37%)	Gaps:	26/199 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GGCVVAMRGKDCVAIATDHRFGIQAQTISTDFKKVFHIGPRMFLGLTGLQTDILTVRDRLMFRKN 72
            |..:..:..||.:.:..|.|..........:..|:..|.|.::....|...|.......:.....
Mouse    43 GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLE 107

  Fly    73 LYETRENREMCPKPFSA--MMSSFLYEHRFGPYFIEPVVAGLDPKTMEPFICNMDLIG------C 129
            |:.....|  .|:..:|  |:...|:  |:..|....:|.|           .:|:.|      .
Mouse   108 LHSLTTGR--LPRVVTANRMLKQMLF--RYQGYIGAALVLG-----------GVDVTGPHLYSIY 157

  Fly   130 PNAPDD---FVVAGTCAEQLYGMCETLWKPDLEPDQLFEVIAQSIVNAFDRDAMSGWGATVYIIE 191
            |:...|   :|..|:.:.....:.|..::||:|.::..::::::|......|..||....:.:|.
Mouse   158 PHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSNIDLCVIS 222

  Fly   192 KDKI 195
            |.|:
Mouse   223 KSKL 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta3	NP_649858.1	proteasome_beta_type_3	6..201	CDD:239728	37/199 (19%)
Psmb7	NP_035317.1	PRE1	41..225	CDD:223711	36/196 (18%)
		proteasome_beta_type_7	44..232	CDD:239732	36/198 (18%)
		Pr_beta_C	236..271	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810