DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta3 and pbs-3

DIOPT Version :9

Sequence 1:	NP_649858.1	Gene:	Prosbeta3 / 41079	FlyBaseID:	FBgn0026380	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_494913.1	Gene:	pbs-3 / 173858	WormBaseID:	WBGene00003949	Length:	204	Species:	Caenorhabditis elegans

Alignment Length:	205	Identity:	113/205 - (55%)
Similarity:	147/205 - (71%)	Gaps:	1/205 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSILAYNGGCVVAMRGKDCVAIATDHRFGIQAQTISTDFKKVFHIGPRMFLGLTGLQTDILTVRD 65
            |||::|.||.||||.|.:||.||:|.|.|.|..||:||.|||..:..::::||.|.|:|..||.:
Worm     1 MSIMSYTGGTVVAMAGDECVCIASDLRIGEQMTTIATDQKKVHKVTDKVYVGLAGFQSDARTVLE 65

  Fly    66 RLMFRKNLYETRENREMCPKPFSAMMSSFLYEHRFGPYFIEPVVAGLDPKTMEPFICNMDLIGCP 130
            ::||||||||.||||.:.|:..|.|:|:..|:||||.||.||:||||| .|.:|:||.||.|||.
Worm    66 KIMFRKNLYELRENRNIKPQVLSEMISNLAYQHRFGSYFTEPLVAGLD-DTNKPYICCMDTIGCV 129

  Fly   131 NAPDDFVVAGTCAEQLYGMCETLWKPDLEPDQLFEVIAQSIVNAFDRDAMSGWGATVYIIEKDKI 195
            :||.|||..||..|.|.|:||..|:.:::||:|||..||||::..:|||.|||||.||.|.|||:
Worm   130 SAPRDFVAVGTGQEYLLGVCENFWRENMKPDELFEATAQSILSCLERDAASGWGAVVYTITKDKV 194

  Fly   196 TERTLKTRMD 205
            ...|:|.|||
Worm   195 NVSTIKARMD 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta3	NP_649858.1	proteasome_beta_type_3	6..201	CDD:239728	106/194 (55%)
pbs-3	NP_494913.1	PRE1	3..193	CDD:223711	104/190 (55%)
pbs-3	NP_494913.1	proteasome_beta_type_3	6..200	CDD:239728	106/194 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156082
Domainoid	1	1.000	209	1.000	Domainoid score	I1659
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2089
Inparanoid	1	1.050	235	1.000	Inparanoid score	I2152
Isobase	1	0.950	-	0	Normalized mean entropy	S357
OMA	1	1.010	-	-		QHG53924
OrthoDB	1	1.010	-	-		D1170036at2759
OrthoFinder	1	1.000	-	-		FOG0003566
OrthoInspector	1	1.000	-	-		oto18553
orthoMCL	1	0.900	-	-		OOG6_101970
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1011
SonicParanoid	1	1.000	-	-		X2440
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790