DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11980 and MYG1

DIOPT Version :9

Sequence 1:	NP_649857.1	Gene:	CG11980 / 41078	FlyBaseID:	FBgn0037652	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_067653.4	Gene:	MYG1 / 60314	HGNCID:	17590	Length:	376	Species:	Homo sapiens

Alignment Length:	345	Identity:	147/345 - (42%)
Similarity:	200/345 - (57%)	Gaps:	24/345 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VTPPKRS------PLWIGTHSGTFHCDELVACFMLKQLDEYKNAEIFRSRDNKALKEKCDIIVDV 76
            |.|||||      |..||||:|||||||.:||.:|:.|.||::|||.|:||.:.| ..|||:|||
Human    31 VPPPKRSRSKLMAPPRIGTHNGTFHCDEALACALLRLLPEYRDAEIVRTRDPEKL-ASCDIVVDV 94

  Fly    77 GGVYDHAKKLYDHHQITFKETFSSVRPDVSEDYNVVRLSSAGLVYCHYGERVIQSILQREKGIKL 141
            ||.||..:..|||||.:|.||.||:.|.....   .:||||||:|.|:|.:::..:|    |...
Human    95 GGEYDPRRHRYDHHQRSFTETMSSLSPGKPWQ---TKLSSAGLIYLHFGHKLLAQLL----GTSE 152

  Fly   142 SPENLQTAFIQIYRNFINELDAIDNGVPMFEGVEPIYKISTHLSARIAKLNPSWQETGVDIEDRF 206
            ....:.|.:.::|.||:.|:||:|||:..:...||.|.::|.||||:|:|||:|.....|.|..|
Human   153 EDSMVGTLYDKMYENFVEEVDAVDNGISQWAEGEPRYALTTTLSARVARLNPTWNHPDQDTEAGF 217

  Fly   207 RQAMDTAGREFVDNVVEVSCSWIPARDHVREALKNAKNVHPTGEILVL-KNFCPWKSHLFDLEKE 270
            ::|||....||:..:.....||:|||..|.|||.....|.|:|||:.| |..||||.||:.||..
Human   218 KRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESG 282

  Fly   271 YKVEGVPKLVVF-----NSGNSWRVAGVPVTPGSYLGRKFLPTPWRGLMDDELCDKASIKDLEFI 330
            ..    |.:.:|     :....||:..||..|.|:..|..||.|||||.|:.|...:.|....|:
Human   283 LS----PPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFV 343

  Fly   331 HHTGFIGGAKTEEAAMLLAK 350
            |.:||.||..|.|.|:.:|:
Human   344 HASGFTGGHHTREGALSMAR 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11980	NP_649857.1	UPF0160	28..352	CDD:281655	140/329 (43%)
MYG1	NP_067653.4	UPF0160	46..366	CDD:308983	140/330 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143318
Domainoid	1	1.000	261	1.000	Domainoid score	I1974
eggNOG	1	0.900	-	-		E1_COG4286
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5853
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3048
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54164
OrthoDB	1	1.010	-	-		D1174497at2759
OrthoFinder	1	1.000	-	-		FOG0004484
OrthoInspector	1	1.000	-	-		oto91587
orthoMCL	1	0.900	-	-		OOG6_102232
Panther	1	1.100	-	-	LDO	PTHR11215
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2348
SonicParanoid	1	1.000	-	-		X3178
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800