DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11980 and Myg1

DIOPT Version :9

Sequence 1:	NP_649857.1	Gene:	CG11980 / 41078	FlyBaseID:	FBgn0037652	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_001005545.1	Gene:	Myg1 / 300258	RGDID:	1359237	Length:	381	Species:	Rattus norvegicus

Alignment Length:	339	Identity:	148/339 - (43%)
Similarity:	200/339 - (58%)	Gaps:	16/339 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PPKR------SPLWIGTHSGTFHCDELVACFMLKQLDEYKNAEIFRSRDNKALKEKCDIIVDVGG 78
            ||||      :|..||||:|||||||.:||.:|:.|.||:||||.|:||.:.| ..|||:|||||
  Rat    33 PPKRPRNNLMAPPRIGTHNGTFHCDEALACALLRLLPEYRNAEIVRTRDPEKL-ALCDIVVDVGG 96

  Fly    79 VYDHAKKLYDHHQITFKETFSSVRPDVSEDYNVVRLSSAGLVYCHYGERVIQSILQREKGIKLSP 143
            .|:..:..|||||.||.||.||:.|.....   .:||||||||.|:|.:::..:|    |.....
  Rat    97 EYNPQRHRYDHHQRTFTETMSSLCPGKPWQ---TKLSSAGLVYLHFGHKLLAQLL----GTSEED 154

  Fly   144 ENLQTAFIQIYRNFINELDAIDNGVPMFEGVEPIYKISTHLSARIAKLNPSWQETGVDIEDRFRQ 208
            ..:.|.:.::|.||:.|:||:|||:..:...||.|.::|.||||:::|||:|.:...|.|..||:
  Rat   155 SVVDTIYDKMYENFVEEVDAVDNGISQWAEGEPRYALTTTLSARVSRLNPTWNQPDQDTEAGFRR 219

  Fly   209 AMDTAGREFVDNVVEVSCSWIPARDHVREALKNAKNVHPTGEILVL-KNFCPWKSHLFDLEKEYK 272
            |||....||:..:.....||:|||..|.|||.....|..:|||:.| |..||||.||:.||.|..
  Rat   220 AMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGGCPWKEHLYHLESELS 284

  Fly   273 VEGVPKLVVF-NSGNSWRVAGVPVTPGSYLGRKFLPTPWRGLMDDELCDKASIKDLEFIHHTGFI 336
            .......|:: :....|||..||..|.|:..|..||.|||||.|:.|...:.|....|:|.:|||
  Rat   285 PTVAITFVIYTDQAGQWRVQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFI 349

  Fly   337 GGAKTEEAAMLLAK 350
            ||..|.|.|:.:|:
  Rat   350 GGHHTREGALNMAR 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11980	NP_649857.1	UPF0160	28..352	CDD:281655	143/325 (44%)
Myg1	NP_001005545.1	UPF0160	46..366	CDD:281655	143/326 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337050
Domainoid	1	1.000	264	1.000	Domainoid score	I1859
eggNOG	1	0.900	-	-		E1_COG4286
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5853
Inparanoid	1	1.050	268	1.000	Inparanoid score	I2954
OMA	1	1.010	-	-		QHG54164
OrthoDB	1	1.010	-	-		D1174497at2759
OrthoFinder	1	1.000	-	-		FOG0004484
OrthoInspector	1	1.000	-	-		oto98657
orthoMCL	1	0.900	-	-		OOG6_102232
Panther	1	1.100	-	-	LDO	PTHR11215
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3178
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770