DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11977 and PI16

DIOPT Version :9

Sequence 1:	NP_649855.3	Gene:	CG11977 / 41076	FlyBaseID:	FBgn0037650	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_001186088.1	Gene:	PI16 / 221476	HGNCID:	21245	Length:	463	Species:	Homo sapiens

Alignment Length:	162	Identity:	33/162 - (20%)
Similarity:	65/162 - (40%)	Gaps:	35/162 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 RKLEWGLGNL------PRAVKFKNIKWDDELSVMAMRVSNQCL-QHTFSPCVNTFLYKDVGESSD 150
            ::|...|.||      |.|....:::||:||:..|...:.||: .|.          |:.|...:
Human    33 KRLMVELHNLYRAQVSPTASDMLHMRWDEELAAFAKAYARQCVWGHN----------KERGRRGE 87

  Fly   151 FVKVQNTSKGFNVISFLNMWFEYHKMMKPSYVNNFPNIAPQDRLIIFANLIYEKNKKMGCGM--- 212
            .: ...|.:|.:|...:..|  :|:  :..|..:....:|......:..:::.|.:::|||.
Human    88 NL-FAITDEGMDVPLAMEEW--HHE--REHYNLSAATCSPGQMCGHYTQVVWAKTERIGCGSHFC 147

  Fly   213 -----VKSGQGRFLTCLFD-----KKIKPNQK 234
                 |:......|.|.::     |..:|.|:
Human   148 EKLQGVEETNIELLVCNYEPPGNVKGKRPYQE 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11977	NP_649855.3	SCP_euk	81..226	CDD:240180	30/147 (20%)
PI16	NP_001186088.1	SCP_HrTT-1	33..166	CDD:240186	30/147 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..281
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..408
		O-glycosylated at one site	386..395
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920