DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11977 and CG43777

DIOPT Version :9

Sequence 1:	NP_649855.3	Gene:	CG11977 / 41076	FlyBaseID:	FBgn0037650	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_001261163.1	Gene:	CG43777 / 14462631	FlyBaseID:	FBgn0264299	Length:	273	Species:	Drosophila melanogaster

Alignment Length:	238	Identity:	61/238 - (25%)
Similarity:	90/238 - (37%)	Gaps:	56/238 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 DYCN--ADICP-ANKKHITCGFKFW-----STKCGRNHEGV----RMSDYRYDIVRNVNNFRRKL 95
            :|||  ...|. ..|||..|..|.:     |||.   |..|    ||.....||   :||.|.|.
  Fly    20 NYCNNKTHKCVLEKKKHFMCHLKDFTVYGNSTKF---HASVPNNMRMQKIALDI---LNNLRNKF 78

  Fly    96 EWG----LGN--LPRAVKFKNIKWDDELSVMAMRVSNQCLQHTFSPCVNTFLYKDVGESSDFVKV 154
            ..|    .||  ..:|.:.:.:.||.||:.|....:: .|....|.|.:|..:..|||:...|..
  Fly    79 AGGELRTKGNKTFAKARRMRQLFWDKELAYMGNNHAS-TLSLKSSQCRSTLRFPHVGEAIALVTP 142

  Fly   155 QNTSKGFNVISFLNMWFEYHKMMKPSYVNNFPNIAPQDRLI------------IFANLIYEKNKK 207
            :..         ||:...|.|...|.:. .:.:::..|.|:            .|.|:|.::..:
  Fly   143 REK---------LNLKEIYSKAFTPMFA-EYQHVSDPDALLHAFDPDRDFQVRHFTNIISDRVSR 197

  Fly   208 MGCGMVKSGQ-------GRFLTCLFDKKIKPNQKLYTTRLNDP 243
            :|||:.....       ..||||.||........:|  :..||
  Fly   198 VGCGVAVGANCNPSIKFCHFLTCYFDFHNMAGSYVY--KAGDP 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11977	NP_649855.3	SCP_euk	81..226	CDD:240180	40/169 (24%)
CG43777	NP_001261163.1	SCP_euk	64..223	CDD:240180	40/172 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020