Protein Alignment CG31100 and HXT1

DIOPT Version :10

• Sequence 1: NP_731299.1
• Gene: CG31100 / 41075
• FlyBaseID: FBgn0051100
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_011962.1
• Gene: HXT1 / 856494
• SGDID: S000001136
• Length: 570
• Species: Saccharomyces cerevisiae
• Alignment Length: 698
• Identity: 124/698 - (17%)
• Similarity: 220/698 - (31%)
• Gaps: 251/698 - (35%)

  Fly     1 MSNGKAATAGATAEKNGSLNDRPLFMQNGNGGRIATSDVEVS----NFRRALPQFLAVSIKNILL 61
            :.:|::........||.|.:|           .::.|.|:.:    |..:.:  ::.|||..:::
Yeast    21 LESGRSKAMNTPEGKNESFHD-----------NLSESQVQPAVAPPNTGKGV--YVTVSICCVMV 72

  Fly    62 FGYGMTLGFPTIVIPAIQGGE------GRSETSGDILLNKDEISWFSSINLICVPLGCLFSGLLT 120
            ...|...|:.|..|.......      |.....|...|:|.......||    ..:||...|::.
Yeast    73 AFGGFIFGWDTGTISGFVAQTDFLRRFGMKHHDGSHYLSKVRTGLIVSI----FNIGCAIGGIVL 133

  Fly   121 QPLGK---RRAMQFVNLPILAAWLMFHFAT--RTEHLYAALCLAGLG-GGL-MEAPVLTYVAEIT 178
            ..||.   ||....|.:.|....::...|:  :....:....::||| ||: :.:|:|  ::|:.
Yeast   134 AKLGDMYGRRIGLIVVVVIYTIGIIIQIASINKWYQYFIGRIISGLGVGGITVLSPML--ISEVA 196

  Fly   179 EPKYRGILSALGTTCVITGVFIQFI-------LGSLMDWRSVAAVSSAFPVITIIMLCFVPESPV 236
            ..:.||.|.:.....:..|:|:.:.       ..:.:.||....:..|:.:..|..:.||||||.
Yeast   197 PSEMRGTLVSCYQVMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMMFVPESPR 261

  Fly   237 WLIREQRFREAVKSLQWLRGWVPEH--------MIEAEFNQL-------YDELITQKAIELSADG 286
            :|:...|..||..||..:....|:|        .|||...::       :.||.|         |
Yeast   262 YLVEAGRIDEARASLAKVNKCPPDHPYIQYELETIEASVEEMRAAGTASWGELFT---------G 317

  Fly   287 IPPPGQRRTLGQRLRMWRKRSFLVPFLLVSFSFFTG----HFSGKTPLQTYAVQIFHTLKAPMNK 347
            .|...||..:|              .::.|....||    .:.|....|...:.         :.
Yeast   318 KPAMFQRTMMG--------------IMIQSLQQLTGDNYFFYYGTIVFQAVGLS---------DS 359

  Fly   348 YHATILLGVAEMLATILGVVLIHFTGKRPLVLVSTVGTGLCFFGTATYAHFLSEVPGFTVNNVVV 412
            :..:|:.||....:|...:..:...|:|..::...||...|:                     ||
Yeast   360 FETSIVFGVVNFFSTCCSLYTVDRFGRRNCLMWGAVGMVCCY---------------------VV 403

  Fly   413 NASSIMPKEGILSQQNISKIFETEQQAIRQETERFTTQLPDIETTTLFDQEIYNRSRRDVVEMMT 477
            .||     .|:
Yeast   404 YAS-----VGV------------------------------------------------------ 409

  Fly   478 TDAPMDTTMWPEPSSSPEPIASSSLAPPSTSVKPPLVEELLLVVPKQEHNYLV------------ 530
                  |.:||.....|.                          .|...|.::
Yeast   410 ------TRLWPNGQDQPS--------------------------SKGAGNCMIVFACFYIFCFAT 442

  Fly   531 -WVPLILLLLSAFFSHLGIRMLPWILIGEVFPAEIRNSASGFAGGVGYIFGFLANKLFLLMLSAL 594
             |.|                 :.:::|.|.||..:::.....|....:|:|||        :|..
Yeast   443 TWAP-----------------IAYVVISECFPLRVKSKCMSIASAANWIWGFL--------ISFF 482

  Fly   595 T--LPGTFAFYASVAFFGTVV-----LYFTLPETEGRTLGEIEAHFSK 635
            |  :.|...||....|.|.:|     ::|.:|||:|.:|.|:...:::
Yeast   483 TPFITGAINFYYGYVFMGCMVFAYFYVFFFVPETKGLSLEEVNDMYAE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31100	NP_731299.1	MFS	51..628	CDD:475125	115/635 (18%)
HXT1	NP_011962.1	Sugar_tr	68..528	CDD:395036	113/634 (18%)